Size dependence of molecular self-assembling in stacked aggregates. 1. NMR investigation of ciprofloxacin self-association

The Journal of Physical Chemistry. B
Ioan Turcu, Mircea Bogdan

Abstract

One of the most important purposes in molecular technologies is the preparation of supramolecular structures by self-assembling processes. The aromatic molecules self-associate mainly in π-π stacked structures with an aggregate size distribution determined by the association equilibrium constants. A general expression for the equilibrium constants K(n,m) which govern the self-association of two aggregates with n and m monomers respectively has been obtained. The model predicts also the concentrations of free monomers, the concentrations of n-mers, and the total concentration of aggregates. (1)H NMR experiments have been used to illustrate the applicability of the proposed model in a particular case: π-stacking self-association of ciprofloxacin in solution.

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Citations

Mar 10, 2016·Physical Chemistry Chemical Physics : PCCP·Maxim P EvstigneevIgor V Golovchenko
Nov 8, 2013·Chemical Communications : Chem Comm·Joydev Hatai, Subhajit Bandyopadhyay
Jul 11, 2013·The Journal of Physical Chemistry. B·Ioan Turcu, Mihaela Mic
May 21, 2014·The Journal of Physical Chemistry. B·Alexandr N SimonovAlan M Bond
Apr 2, 2019·Physical Chemistry Chemical Physics : PCCP·Anatoly S BuchelnikovMaxim P Evstigneev
Jul 16, 2014·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Andrew A MosunovMaxim P Evstigneev
Feb 7, 2018·Dental Materials : Official Publication of the Academy of Dental Materials·Yasaman DelavizJ Paul Santerre

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