Size-dependent dielectrophoretic crossover frequency of spherical particles

Biomicrofluidics
Ping-You WengJia-Yang Juang

Abstract

Dielectrophoresis (DEP) has been extensively used in lab-on-a-chip systems for trapping, separating, and manipulating of micro particles suspended in a liquid medium. The most widely used analytic model, the dipole model, provides an accurate prediction on the crossover frequency of submicron particles, but cannot explain the significant drop in crossover frequency of larger particles. Here, we present numerical simulations using the Maxwell stress tensor (MST) and finite element method to study the size effect of the DEP crossover frequency of spherical polystyrene particles suspended in de-ionized water. Our results show that the surface conductance due to the electrical double layer plays a key role, and the size dependency of crossover frequency obtained by the MST method agrees reasonably well with published experimental data. The exponents of the power law are approximately -1.0 and -4.3 for smaller (diameter < 4.6 μm) and larger particles (diameter  > 4.6 μm), respectively. The free surface charge distribution reveals that the charge begins accumulating on the particle equator for particle diameters larger than a critical diameter of 4.6 μm, a result not captured by the dipolar approximation. This method may be extended ...Continue Reading

References

Jan 1, 1992·Physics in Medicine and Biology·A M Campbell, D V Land
May 26, 1998·Analytical Chemistry·S FiedlerG Fuhr
Apr 9, 1999·Biotechnology Progress·M P Hughes, H Morgan
Dec 23, 1999·Journal of Colloid and Interface Science·M P HughesM F Flynn
Aug 5, 2003·Physics in Medicine and Biology·Juliana JohariMichael P Hughes
Apr 20, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·T B JonesD J Yao
May 2, 2007·Bioelectromagnetics·A SanchisJ M Miranda
Aug 21, 2009·Biomicrofluidics·Ming-Tzo WeiH Daniel Ou-Yang

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Citations

Mar 31, 2017·Journal of Biomedical Optics·Syed Abdul Mannan KirmaniIvan T Lima
Apr 24, 2018·Applied Sciences·E DuJia Liu
Oct 28, 2019·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Clyde MideletMartinus H V Werts
Jan 8, 2020·Micromachines·Fleming Dackson GudaguntiIvan T Lima
Nov 17, 2020·Electrophoresis·Benjamin SarnoStuart D Ibsen
Mar 7, 2021·Biosensors·Anthony T GiduthuriSoumya K Srivastava
Jun 30, 2021·Biomedical Microdevices·Mohammad Rizwen Ur RahmanWoo-Jin Chang

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