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Size Matters: Arginine-Derived Peptides Targeting the PSMA Receptor Can Efficiently Complex but Not Transfect siRNA

Molecular Therapy. Nucleic Acids

Oct 23, 2019

Christopher N CultraraDavid Sabatino

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Abstract

Oligoarginine sequences conjugated to a short cancer-targeting peptide (CTP) selective for the prostate-specific membrane antigen (PSMA) receptor was developed for selective small interfering RNA (siRNA) delivery to a human metastatic/castration-resistant prostate cancer (PCa) cell line...read more

Mentioned in this Paper

Anions
Gel
Heparin
Peptides
Cell Line, Tumor
Surface
Malignant Neoplasm of Prostate
Transmission Electron Microscopy
Liquid Chromatography Mass Spectrometry
RNA, Small Interfering
2
1
2
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Size Matters: Arginine-Derived Peptides Targeting the PSMA Receptor Can Efficiently Complex but Not Transfect siRNA

Molecular Therapy. Nucleic Acids

Oct 23, 2019

Christopher N CultraraDavid Sabatino

PMID: 31739211

DOI: 10.1016/j.omtn.2019.10.013

Abstract

Oligoarginine sequences conjugated to a short cancer-targeting peptide (CTP) selective for the prostate-specific membrane antigen (PSMA) receptor was developed for selective small interfering RNA (siRNA) delivery to a human metastatic/castration-resistant prostate cancer (PCa) cell line...read more

Mentioned in this Paper

Anions
Gel
Heparin
Peptides
Cell Line, Tumor
2
1
2

Related Papers

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