Size of left cardiac chambers correlates with cerebral microembolic load in open heart operations.

Cardiology Research and Practice
Elena Z GolukhovaAlexey V Begachev

Abstract

Background. Microemboli are a widely recognized etiological factor of cerebral complications in cardiac surgery patients. The present study was aimed to determine if size of left cardiac chambers relates to cerebral microembolic load in open heart operations. Methods. Thirty patients participated in the study. Echocardiography was performed in 2-3 days before surgery. A transcranial Doppler system was used for registering intraoperative microemboli. Results. Preoperative left atrium and left ventricular end-systolic and end-diastolic sizes significantly correlated with intraoperative microembolic load (rs = 0.48, 0.57 and 0.53, Ps < .01, resp.). The associations between left ventricular diameters and number of cerebral microemboli remained significant when cardiopulmonary bypass time was included as a covariate into the analysis. Conclusions. The present results demonstrate that increased size of left heart chambers is an influential risk factor for elevated cerebral microembolic load during open heart operations. Mini-invasive surgery and carbon dioxide insufflation into wound cavity may be considered as neuroprotective approaches in patients with high risk of cerebral microembolism.

References

Feb 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·R E ClarkG J Magovern
Jun 27, 2003·Journal of Cardiothoracic and Vascular Anesthesia·Mikael Persson, Jan Van Der Linden
Jan 31, 2004·The Journal of Thoracic and Cardiovascular Surgery·Jan BuceriusFriedrich W Mohr
Jun 3, 2004·The Journal of Thoracic and Cardiovascular Surgery·Yasir Abu-OmarDavid P Taggart
Mar 9, 2005·Perfusion·Rosendo A RodriguezHoward J Nathan
May 28, 2005·Seminars in Cardiothoracic and Vascular Anesthesia·Hilary P GrocottFerenc Puskas
Sep 14, 2006·Cerebrovascular Diseases·Leo A BokeriiaSvetlana N Kazanovskaya
Oct 24, 2006·Anesthesia and Analgesia·Kenji YoshitaniG Burkhard Mackensen
Jan 2, 2007·Anesthesiology·Marek A MirskiThomas J K Toung
Jan 29, 2008·The Annals of Thoracic Surgery·Sven MartensAnton Moritz
Jun 30, 2009·The Annals of Thoracic Surgery·Leo A BokeriiaAnna G Polunina
Jan 23, 2010·Perfusion·James L RudolphEdward R Marcantonio

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BETA
coronary artery bypass

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SPSS

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