Size overlap between benign melanocytic choroidal nevi and choroidal malignant melanomas

Investigative Ophthalmology & Visual Science
J J AugsburgerAdeel Shaikh

Abstract

To estimate size overlap between large choroidal nevi and small choroidal melanomas by using plotted frequency distributions of tumor size. Frequency distributions of largest linear basal diameter (LBD) and thickness (TH) of choroidal nevi and melanomas were plotted from published data and cases in the senior author's practice. Relative frequencies of choroidal nevi and melanomas were estimated from published data. Relative frequency distributions of the tumors were plotted to illustrate the extent of overlap between them. Comparison of plotted frequency distribution curves for thickness indicated that there were approximately 125 nevi for every melanoma in the TH range 1.5 to 2 mm, approximately 25 nevi for every melanoma in the TH range 2 to 2.5 mm, and approximately 5 nevi for every melanoma in the TH range 2.5 to 3 mm. Similarly, comparison of the plotted frequency distribution curves for LBD of these tumor types indicated that there were approximately 70 nevi for every choroidal melanoma in the LBD range 5 to 6 mm, approximately 10 nevi for every melanoma in the LBD range 6 to 7 mm, and approximately 3 nevi for every melanoma in the LBD range 7 to 8 mm. Because of the markedly greater cumulative lifetime incidence of choro...Continue Reading

Citations

Feb 6, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Peter MalocaPascal W Hasler
Mar 30, 2010·American Journal of Ophthalmology·Daniel J WeisbrodE Rand Simpson
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Jan 7, 2021·Familial Cancer·Timothy W GroselColleen M Cebulla
Jun 18, 2021·Journal of Experimental & Clinical Cancer Research : CR·Prisca BustamanteJulia V Burnier

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