Skeletal Manifestations of TB in Modern Human Remains

Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists
Maryna Steyn, Jenifer Buskes

Abstract

Paleopathologists study the presence of diseases in the past, and as such have a vast knowledge of skeletal changes associated with different conditions. Tuberculosis is one of the most studied diseases, and still remains a major health problem today. Its manifestations in past populations have been extensively described, but less is known about its bony involvement in the post-antibiotic era. The aim of this study was to assess the frequency and manifestations of skeletal lesions in the post-antibiotic era in a xxxx sample, and compare it to that found before the introduction of antibiotics. Skeletons of 205 individuals from modern skeletal collections and who are known to have died from TB were assessed. It was found that 39.2% of all individuals dying in the post-antibiotic era showed skeletal changes that could be associated with TB, while another 27.5% showed non-specific changes. The highest incidences were found in individuals who died after 1985, when co-infection with HIV and drug resistance became common. While, as expected, vertebral and rib changes were the most common, the number of individuals who showed changes to the skull, and specifically intra-cranially, was surprising. These could most probably be associated...Continue Reading

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