Skeletal metastasis in patients with gastric cancer

Clinical Orthopaedics and Related Research
Hirofumi NakanishiHideki Yoshikawa

Abstract

To clarify metastatic patterns, and histologic and radiologic features in skeletal metastases from gastric cancer, 48 patients were retrospectively analyzed. The mean age of the patients at the time of diagnosis of gastric cancer was 59 years. In 31 patients with a history of the radical surgery, the mean interval between surgery and diagnosis of skeletal metastasis was 14 months. The mean duration between diagnosis of skeletal metastasis and death was 60 days. Scintigraphic assessment showed that solitary osseous lesions were found in four patients, whereas the remaining 44 had multiple skeletal lesions. In 28 patients with bone-only metastases with absence of visceral metastases, a higher incidence of thoracolumbar metastases at the level nearest the stomach was found. The incidence of skeletal metastasis in each histologic type was intestinal in 19 and diffuse in 29. Radiologic examination revealed that the ratio between the presence and the absence of osteosclerosis was 1:2. Osteosclerosis was seen in three of 19 patients with intestinal type metastasis, whereas with the diffuse type 13 of 29 patients had osteosclerosis.

References

May 1, 1983·The Japanese Journal of Surgery·K Yoshikawa, H Kitaoka
May 2, 2002·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Shu-Ichi HironakaShigeaki Yoshida
Jun 29, 2002·Yonsei Medical Journal·Yoon-Sok ChungLorraine A Fitzpatrick
Mar 1, 1965·Radiology·R ARKLESS

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Citations

Jun 22, 2007·Clinical Nuclear Medicine·Masamichi Koyama, Mitsuru Koizumi
Oct 21, 2014·Journal of Gastric Cancer·Fatma Paksoy TurkozSuayib Yalcin
Jan 24, 2018·World Journal of Gastroenterology : WJG·Young Jin ChoiHyo Yung Yun
Aug 16, 2014·The Journal of Manual & Manipulative Therapy·Lance M MabryJohn M Tonarelli
Jul 6, 2021·Rare Tumors·Anthony L NguyenHamid Mirshahidi

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