PMID: 8458814Feb 1, 1993Paper

Skeletal muscle myosin heavy chain composition and resistance training

Journal of Applied Physiology
G R AdamsG A Dudley

Abstract

We recently reported that 19 wk of heavy resistance training caused a decrease in the percentage of type IIb and an increase in the percentage of type IIa fibers as determined by qualitative histochemical analyses of myofibrillar adenosinetriphosphatase activity of biopsies of musculus vastus lateralis (Hather et al. Acta Physiol. Scand. 143: 177-185, 1991). These data were interpreted to suggest that resistance training had caused transformation among the fast-twitch fiber subtypes. To more clearly establish the influence of resistance training on muscle fiber composition, biopsies from the original study were analyzed biochemically for myosin heavy chain (MHC) composition by use of sodium dodecyl sulfate-polyacrylamide gel electrophoresis and histochemically for fiber types by use of myofibrillar adenosinetriphosphatase activity. The results show that after training (n = 13), IIb MHC composition decreased (P < 0.05) from 19 +/- 4 to 7 +/- 1%. IIa MHC, in contrast, increased (P < 0.05) from 48 +/- 3 to 60 +/- 2%. These responses were essentially mirrored by alterations in fiber type distribution. The percentage of type IIb fibers decreased (P < 0.05) from 18 +/- 3 to 1 +/- 1%, whereas the percentage of type IIa fibers increase...Continue Reading

Citations

Jan 1, 1997·Journal of Applied Physiology·H E BergP A Tesch
Jan 1, 1997·Journal of Applied Physiology·V J CaiozzoK M Baldwin
Oct 20, 2001·Journal of Applied Physiology·D L WilliamsonS W Trappe
Aug 27, 2004·Acta Physiologica Scandinavica·B FriedmannR Billeter
Dec 6, 2005·The European Journal of Neuroscience·T van WesselT M G J van Eijden
Jan 31, 2006·Research in Sports Medicine·Brian K SchillingLoren Z F Chiu
Aug 5, 2008·European Journal of Applied Physiology·Valeria ParenteRoberto Bottinelli
Oct 5, 2010·Experimental Physiology·Robert M ErskineHans Degens
Nov 14, 2012·European Journal of Orthodontics·Anna M ÖdmanMark P Lewis
Jul 24, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Stian EllefsenBent R Rønnestad
Jan 1, 1995·Pflügers Archiv : European journal of physiology·A SaboridoA Megías
Jan 1, 1996·European Journal of Applied Physiology and Occupational Physiology·J JürimäeM T McEniery
Feb 10, 1999·The American Journal of Physiology·D S O'NeillJ A Houmard
Jun 11, 1998·Journal of Applied Physiology·F HaddadK M Baldwin
Jul 7, 2000·Muscle & Nerve·J L Andersen, P Aagaard
May 8, 2002·Muscle & Nerve·Stephen D R HarridgeMichael Kjaer
Jun 5, 2003·Medicine and Science in Sports and Exercise·Todd C ShoepeJeffrey J Widrick
Jun 8, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Jana RudnickDieter Blottner
Dec 28, 2002·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·J A M Korfage, T M G J Van Eijden
Jun 24, 2004·Journal of Aging and Physical Activity·Ando PehmeTeet Seene
Aug 13, 2010·European Journal of Applied Physiology·Robert M ErskineHans Degens
May 8, 2008·European Journal of Applied Physiology·Nikolaos KesidisKonstantinos Mandroukas
Nov 18, 2010·Muscle & Nerve·Bettina A GentryMarybeth Brown
Apr 9, 2011·Biotechnology Letters·S PasseyM P Lewis
Sep 8, 2012·Journal of Strength and Conditioning Research·Michael D RobertsChad M Kerksick
Sep 18, 2012·Journal of Applied Physiology·Zachary Barrett-O'KeefeRussell S Richardson
Nov 5, 2011·Journal of Applied Physiology·Paul M GordonEric P Hoffman
Jan 23, 2016·The Journal of Experimental Biology·Clark J Cotton
Jul 1, 2017·Journal of Applied Physiology·Charles A StuartMichael H Stone
Feb 22, 2018·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Randall F D'SouzaCameron J Mitchell
Feb 17, 2019·Sports·Angeliki-Nikoletta StasinakiGerasimos Terzis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.