Skeletal status in adolescents with end-stage renal failure: a longitudinal study

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Wojciech PluskiewiczD Karasek

Abstract

In a longitudinal study, bone status was assessed in adolescents and young adults aged 15.3+/-3.4 years at the onset of the study with end-stage renal failure (ESRF). The group consisted of 18 subjects (11 females and seven males), of whom nine patients were on hemodialysis and nine patients on peritoneal dialysis. Six patients were previous or current glucocorticoid (GCS) users. Renal failure was recognized before 6.1+/-4.1 years, and dialysis was performed for 3.0+/-2.0 years. Follow-up took placed 8.6+/-0.8 and 21.7+/-2.5 months later, and the following data were collected: bone mineral density (BMD) at the spine (s-BMD) and total body (TB-BMD) using DPX-L (Lunar, USA); quantitative ultrasound by DBM 1200 (IGEA, Italy) at the hand phalanges (Amplitude-dependent Speed of Sound, Ad-SoS), serum concentration of i-PTH, total calcium, ionized calcium and phosphate. Tanner stages were also evaluated. The mean values of BMD measurements and Ad-SoS were stable during a period of observation, and a mean Z-score for TB-BMD was significantly lower at the third versus baseline value (-1.87+/-1.75 versus -1.49+/-1.53, P<0.05). Z-scores for s-BMD and Ad-SoS decreased non-significantly. Changes in s-BMD and TB-BMD Z-scores were influenced ...Continue Reading

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Citations

Apr 14, 2007·Pediatric Radiology·Larry A BinkovitzMaria J Henwood
Sep 29, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A MussaA Corrias
Oct 28, 2006·The British Journal of Radiology·Z P HalabaU Drzewiecka
Sep 16, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Simon WallerLesley Rees
Feb 22, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Lindsay M GriffinMary B Leonard
May 4, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Wojciech Pluskiewicz
Oct 4, 2012·Kidney International·Anne TsampalierosMary B Leonard
Apr 17, 2012·Ultrasound in Medicine & Biology·Joanna ZywiecJanusz Gumprecht
Jul 9, 2010·Radiologic Clinics of North America·Giuseppe GuglielmiWilfred C G Peh
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Aug 5, 2009·European Journal of Radiology·Giuseppe Guglielmi, Francesca de Terlizzi
Apr 7, 2007·Ultrasound in Medicine & Biology·W PluskiewiczR Kuźniewicz
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Oct 19, 2006·Ultrasound in Medicine & Biology·Wojciech PluskiewiczPiotr Adamczyk
Aug 31, 2006·The Journal of Pediatrics·Wojciech Pluskiewicz, Zenon Halaba
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Sep 30, 2016·Expert Review of Gastroenterology & Hepatology·Katarzyna Bąk-DrabikWojciech Pluskiewicz
May 25, 2016·Current Opinion in Nephrology and Hypertension·Michelle R Denburg
Aug 22, 2018·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P AdamczykW Pluskiewicz

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