Skeletal stem cells

Development
Paolo Bianco, Pamela G Robey

Abstract

Skeletal stem cells (SSCs) reside in the postnatal bone marrow and give rise to cartilage, bone, hematopoiesis-supportive stroma and marrow adipocytes in defined in vivo assays. These lineages emerge in a specific sequence during embryonic development and post natal growth, and together comprise a continuous anatomical system, the bone-bone marrow organ. SSCs conjoin skeletal and hematopoietic physiology, and are a tool for understanding and ameliorating skeletal and hematopoietic disorders. Here and in the accompanying poster, we concisely discuss the biology of SSCs in the context of the development and postnatal physiology of skeletal lineages, to which their use in medicine must remain anchored.

References

Sep 1, 1991·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·A I Caplan
Apr 1, 1988·British Journal of Haematology·P BiancoE Bonucci
Jul 5, 1968·Science·M Tavassoli, W H Crosby
Feb 1, 1993·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·P BiancoP G Robey
Sep 1, 1997·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S A KuznetsovP G Robey
Aug 26, 1998·Matrix Biology : Journal of the International Society for Matrix Biology·P BiancoR Cancedda
Dec 9, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·M RiminucciP Bianco
Apr 2, 1999·Science·M F PittengerD R Marshak
May 13, 1999·Nature Genetics·W BiB de Crombrugghe
Aug 13, 1999·Critical Reviews in Eukaryotic Gene Expression·P BiancoP G Robey
Apr 6, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·H D NahT Kirsch
Oct 14, 2000·Annual Review of Cell and Developmental Biology·B R OlsenW Wang
May 16, 2003·Nature·Henry M Kronenberg
Nov 12, 2003·The Journal of Cell Biology·Kenn HolmbeckHenning Birkedal-Hansen
Aug 16, 2005·Science·Jeong-Ho HongMichael B Yaffe
May 11, 2006·Journal of Cell Science·Lindolfo da Silva MeirellesNance Beyer Nardi
Apr 10, 2008·Cell Stem Cell·Paolo BiancoPaul J Simmons
Oct 16, 2008·Cellular and Molecular Life Sciences : CMLS·S MuruganandanC J Sinal
Mar 5, 2010·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Amer MahmoodMoustapha Kassem
Aug 13, 2010·Nature·Simón Méndez-FerrerPaul S Frenette
Nov 26, 2010·Nature Medicine·Damian MediciBjorn R Olsen
Jan 8, 2011·Aging Cell·Moustapha Kassem, Pierre J Marie
Jul 13, 2011·Bone·Basem M Abdallah, Moustapha Kassem
Jul 30, 2011·Tissue Engineering. Part B, Reviews·Pamela Gehron Robey
May 23, 2013·Advances in Experimental Medicine and Biology·David Cook, Paul Genever
Feb 1, 2014·Methods in Molecular Biology·Pamela Gehron RobeyPaolo Bianco
Aug 6, 2014·Proceedings of the National Academy of Sciences of the United States of America·Liu YangKathryn S E Cheah
Aug 26, 2014·Annual Review of Cell and Developmental Biology·Paolo Bianco
Jan 17, 2015·Cell·Charles K F ChanMichael T Longaker

❮ Previous
Next ❯

Citations

Feb 13, 2016·Blood·Krisztian Nemeth, Eva Mezey
Dec 18, 2015·International Journal of Hematology·Yo Mabuchi, Yumi Matsuzaki
Mar 1, 2016·Scientific Reports·Keiko MaedaMasahide Takahashi
Jan 30, 2016·Stem Cells International·Wessam E Sharaf-EldinNagwa El-Badri
Dec 5, 2015·Frontiers in Cellular Neuroscience·Wanda LattanziLuca Bonfanti
Apr 5, 2016·Stem Cell Research·Giulio CossuMichele De Luca
Jun 11, 2015·Journal of Cellular Physiology·Seyed Hossein BassirGiuseppe Intini
Mar 24, 2016·Stem Cells International·Satoru MorikawaTaneaki Nakagawa
Jul 6, 2016·Frontiers in Surgery·James HoltonMartin Snow
Jul 26, 2016·Frontiers in Endocrinology·Pierre HardouinStéphanie Lucas
Sep 3, 2016·Clinical Oral Investigations·Antoine BerbériKazem Zibara
Nov 2, 2016·Frontiers in Cell and Developmental Biology·Marina MontaliSimone Pacini
Dec 28, 2016·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Danielle R Rux, Deneen M Wellik
Nov 12, 2016·Journal of Dental Research·I VidovicM Mina
Jun 13, 2017·Nature Reviews. Immunology·Genevieve M CraneSean J Morrison
Jul 1, 2017·The Journal of Craniofacial Surgery·Matthew P MurphyCharles K F Chan
Dec 23, 2017·Materials·Bach Quang LeVanessa Lydia Simone LaPointe
Sep 7, 2017·Antioxidants & Redox Signaling·Agnieszka LangrzykJózef Dulak
Oct 12, 2017·Journal of Dental Research·J NathanM C Embree
Feb 18, 2018·The Journal of Experimental Medicine·Ander AbarrategiDominique Bonnet
Dec 13, 2017·Frontiers in Physiology·Daniel H DoroKaren J Liu
Jun 2, 2016·Therapeutic Advances in Musculoskeletal Disease·Elena A JonesDimitrios Kouroupis
Jul 7, 2016·Development·Paul T Sharpe
Apr 21, 2016·Development·Maria Paola SantiniJason C Kovacic
Aug 4, 2018·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Joshua N Farr, Maria Almeida
Oct 25, 2017·Plastic and Reconstructive Surgery. Global Open·Matthew P MurphySean M Carroll
Sep 1, 2018·Tissue Engineering. Part B, Reviews·Dimitrios KouroupisDiego Correa
Sep 19, 2018·Integrative Biology : Quantitative Biosciences From Nano to Macro·Catarina Costa MouraSumeet Mahajan
Aug 29, 2018·The Journal of Biological Chemistry·Brianna H SharesRoman A Eliseev
Feb 24, 2018·Nature Communications·Oriane Duchamp de LagenesteCéline Colnot
Feb 27, 2019·Current Osteoporosis Reports·Robert J PignoloAbhishek Chandra
May 11, 2019·Orthodontics & Craniofacial Research·Zeena QiryaqozLuis G Villa-Diaz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of the American Dental Association
Pamela G Robey, Paolo Bianco
Methods in Molecular Biology
Benjamin J Frisch, Laura M Calvi
The Australasian Nurses Journal
A Braendler
The Australasian Nurses Journal
M Hollis
© 2022 Meta ULC. All rights reserved