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SKI2 mediates degradation of RISC 5'-cleavage fragments and prevents secondary siRNA production from miRNA targets in Arabidopsis

Nucleic Acids Research

Oct 16, 2015

Anja BranscheidPeter Brodersen

Abstract

Small regulatory RNAs are fundamental in eukaryotic and prokaryotic gene regulation. In plants, an important element of post-transcriptional control is effected by 20-24 nt microRNAs (miRNAs) and short interfering RNAs (siRNAs) bound to the ARGONAUTE1 (AGO1) protein in an RNA induced si...read more

Mentioned in this Paper

Biochemical Pathway
Small Nuclear RNA
EIF2C1 protein, human
SKI3 protein, Arabidopsis
RAX3 protein, Arabidopsis
Post-Transcriptional Regulation
SCPEP1 gene
Arabidopsis
RNA, Small Interfering
Transcription, Genetic
6
77
Paper Details
References
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  • Citations9
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  • References64
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SKI2 mediates degradation of RISC 5'-cleavage fragments and prevents secondary siRNA production from miRNA targets in Arabidopsis

Nucleic Acids Research

Oct 16, 2015

Anja BranscheidPeter Brodersen

PMID: 26464441

DOI: 10.1093/nar/gkv1014

Abstract

Small regulatory RNAs are fundamental in eukaryotic and prokaryotic gene regulation. In plants, an important element of post-transcriptional control is effected by 20-24 nt microRNAs (miRNAs) and short interfering RNAs (siRNAs) bound to the ARGONAUTE1 (AGO1) protein in an RNA induced si...read more

Mentioned in this Paper

Biochemical Pathway
Small Nuclear RNA
EIF2C1 protein, human
SKI3 protein, Arabidopsis
RAX3 protein, Arabidopsis
Post-Transcriptional Regulation
SCPEP1 gene
Arabidopsis
RNA, Small Interfering
Transcription, Genetic
6
77

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RNA-induced Silencing Complex (Keystone)

The RNA-induced Silencing Complex mediates gene silencing through direct mRNA degradation or translational inhibition. Discover the latest research on the RNA-induced Silencing Complex in this feed.

RNA-induced Silencing Complex

The RNA-induced Silencing Complex mediates gene silencing through direct mRNA degradation or translational inhibition. Discover the latest research on the RNA-induced Silencing Complex here.

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Genes & Development

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

Genes & DevelopmentJuly 3, 2004
Katsutomo OkamuraMikiko C Siomi
Nucleic Acids Research

The miRNA pathway limits AGO1 availability during siRNA-mediated PTGS defense against exogenous RNA

Nucleic Acids ResearchAugust 5, 2011
Angel Emilio Martínez de AlbaHervé Vaucheret
Paper Details
References
  • References64
  • Citations9
12345...
  • References64
  • Citations9
1
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