PMID: 9557796Apr 29, 1998Paper

Skin as the primary site of Hodgkin's disease: a case report of primary cutaneous Hodgkin's disease and review of its relationship with non-Hodgkin's lymphoma

The American Journal of Dermatopathology
J Guitart, D Fretzin

Abstract

We report an elderly patient who presented with a single cutaneous nodule of primary cutaneous Hodgkin's disease (PCHD). Reed-Sternberg cells, expressing CD30 and CD15, but not leukocyte common antigen (CD45RB), were identified in the neoplastic cells. Southern blot analysis failed to detect T-cell receptor or immunoglobulin gene rearrangement. A work-up for systemic disease at the time of presentation was negative, supporting the diagnosis of PCHD. Nevertheless, 1 year later, the disease course was complicated by the development of nodal HD and nonHodgkin's lymphoma (NHL). This case report supports the existence of this rare, but distinct, cutaneous tumor.

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Citations

Jun 10, 2004·The Journal of Dermatology·Suna ErkiliçCelalettin Camci
Jul 11, 2012·Current Hematologic Malignancy Reports·Nicholas A Barber, Philip J Bierman
Aug 28, 2003·Journal of the European Academy of Dermatology and Venereology : JEADV·V Stadie, W C H Marsch
Mar 31, 1999·The Australasian Journal of Dermatology·J A Pagliaro, S I White
Jun 17, 2006·Cancer Investigation·Vassilios PerifanisVassilia Garipidou
Oct 3, 2006·The American Journal of Dermatopathology·Dmitry V KazakovWerner Kempf
Mar 10, 2016·The American Journal of Dermatopathology·Giang HuongCynthia M Magro
Jan 26, 2011·Journal of Cutaneous Pathology·Begoña VieitesFrancisco Carvajo
Jul 12, 2014·The American Journal of Dermatopathology·Mar Llamas-VelascoAmaro García-Diez
Sep 23, 2009·The American Journal of Dermatopathology·Keiji TaneseSyunichi Miyakawa
Nov 21, 2007·Dermatologic Clinics·Gabriela Rolz-Cruz, Caroline C Kim

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