Skin biology

Dermatologic Therapy
Charlotte HwaDavid E Cohen

Abstract

The development of topical drug delivery systems has recently gained significant interest due to the ease of administration and lesser risks of systemic toxicity. The development of these new technologies utilizes the properties of the structure and function of the skin. The stratum corneum plays the largest role in affecting drug permeation, as the corneocytes and lipid matrix in this layer effectively prevent the diffusion of large molecules. In this review, we introduce the structure and function of the skin as it relates to topical drug delivery.

References

Mar 1, 1978·The Journal of Pharmacy and Pharmacology·M I ForemanI P Kelly
May 1, 1979·International Journal of Dermatology·E A Bauer, J Uitto
Mar 1, 1992·The Journal of Investigative Dermatology·G K MenonP M Elias
Feb 1, 1992·The Journal of Clinical Investigation·S H LeeK R Feingold
Jun 1, 1991·The Journal of Investigative Dermatology·K P WilhelmH I Maibach
Apr 1, 1991·The Journal of Investigative Dermatology·R O Potts, M L Francoeur
May 1, 1990·Journal of the American Academy of Dermatology·D J Hogan, H I Maibach
Jan 1, 1986·Biology of the Neonate·N J Evans, N Rutter
Oct 1, 1971·The Journal of Pediatrics·R L Nachman, N B Esterly
Jan 1, 1969·The Journal of Investigative Dermatology·R J ScheupleinD J MacFarlane
Nov 1, 1965·The Journal of Investigative Dermatology·R J Scheuplein
Feb 1, 1967·The Journal of Investigative Dermatology·R J Feldmann, H I Maibach
May 1, 1983·Journal of the American Academy of Dermatology·R C WesterH I Maibach
May 1, 1983·Journal of the American Academy of Dermatology·J A Fairley, J E Rasmussen
Jan 1, 1981·Current Problems in Dermatology·G F Odland, K Holbrook
Apr 1, 1994·Archives of Dermatology·S MottaR Caputo
Jan 1, 1993·Current Problems in Dermatology·R C Wester, H I Maibach
Jan 1, 1996·The Journal of Investigative Dermatology·D A Van HalJ A Bouwstra
Jan 1, 1997·Skin Pharmacology : the Official Journal of the Skin Pharmacology Society·G K Menon, P M Elias
Aug 12, 1998·The Journal of Investigative Dermatology·Y N KaliaR H Guy
Dec 5, 1998·Microscopy Research and Technique·M HaftekD Schmitt
Jun 6, 2000·Experimental Dermatology·J D Bos, M M Meinardi
May 19, 2001·Pediatric Dermatology·F GiustiS Seidenari
Sep 21, 2001·The Journal of Investigative Dermatology·G S PilgramH K Koerten
May 16, 2002·American Journal of Clinical Dermatology·Frank RippkeHans-Joachim Schwanitz
Jul 1, 1962·The British Journal of Dermatology·E CRONIN, R B STOUGHTON
Jul 1, 1963·Archives of Dermatology·C F VICKERS
Jan 20, 2004·Dermatologic Therapy·Clive R Harding
Jun 22, 2005·Journal of the American Academy of Dermatology·Xinfan HuangLincoln Krochmal
Aug 3, 2005·American Journal of Clinical Dermatology·Myeong Jun Choi, Howard I Maibach
Aug 16, 2005·The Journal of Investigative Dermatology·Alexa TeichmannJürgen Lademann
Oct 14, 2005·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Jeanette M Waller, Howard I Maibach
Jan 31, 2006·Nature Genetics·Frances J D SmithW H Irwin McLean
Jul 4, 2006·The Journal of Allergy and Clinical Immunology·Michael J CorkRachid Tazi-Ahnini
Jan 23, 2009·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·T Tanner, R Marks
Mar 11, 2010·Handbook of Experimental Pharmacology·Hans Christian Korting, Monika Schäfer-Korting
Jun 1, 1983·The Journal of Investigative Dermatology·P M Elias
Oct 1, 1946·Physiological Reviews·H O CALVERYE P LAUG

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Citations

Nov 26, 2015·Expert Opinion on Drug Delivery·Ibrahim A AljuffaliJia-You Fang
Jun 4, 2014·Journal of Drug Targeting·H KhanZ Ahmad
Nov 6, 2012·Progress in Lipid Research·Alexandra C Kendall, Anna Nicolaou
Feb 13, 2016·Photodermatology, Photoimmunology & Photomedicine·Christoffer V NissenHans Christian Wulf
Jun 28, 2016·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Woan-Ruoh LeeJia-You Fang
Jun 26, 2017·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·S MünchR H H Neubert
Feb 23, 2020·Diagnostics·Shu-Hua KuoChao-Min Cheng
Sep 8, 2017·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·R Daniels
Mar 6, 2021·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Shuai ZhangLiang Fang
Jun 8, 2021·Biochimie·Inês V da SilvaGraça Soveral

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