PMID: 7017012Mar 1, 1981Paper

Skin calcium binding protein is localized in the cytoplasm of the basal layer of the epidermis

The Journal of Investigative Dermatology
J H SauratS Balsan

Abstract

Using a serum raised in rabbits against a calcium binding protein extracted from rat skin, the cutaneous localization of this protein was studied by indirect immunofluorescence. The skin calcium binding immunoreactivity was found in the epidermis but not in the dermis; it was localized in the cytoplasm of the basal cell layer of both skin and malpighian mucosa. There was not species specificity; this allowed the tracing of the protein in human epidermis as well where it was also expressed only in the basal cells. This is the first demonstration of the unique localization of a specific protein within the cytoplasm of the basal cell layer of the epidermis. This localization may help to elucidate the physiological role of this protein.

References

May 29, 1979·Archives of Dermatological Research·L Galoppin, J H Saurat
Feb 1, 1978·The British Journal of Dermatology·J H SauratE Gluckman
Aug 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·R L MorrisseyD D Bikle
Mar 9, 1979·Cell and Tissue Research·P MarcheP Cassier
Jan 1, 1976·Current Problems in Dermatology·E Christophers, E B Laurence
Feb 1, 1970·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·A N Taylor, R H Wasserman
Mar 10, 1980·FEBS Letters·D LaouariS Balsan

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Citations

Feb 1, 1983·Journal of Oral Pathology·B B SinghM B Ringler
Sep 1, 1984·Cell and Tissue Kinetics·M F Kulesz-MartinJ S Bertram
Jul 27, 2010·Archives of Dermatological Research·Jeannette TothPecorella Irene
Feb 1, 1983·Journal of Cutaneous Pathology·J Thivolet, M Faure
Feb 6, 1999·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·J S WalshH W Randle
Aug 1, 1984·The British Journal of Dermatology·P J Dykes, R Marks
Jan 1, 1982·Archives of Dermatological Research·P J DykesR Marks
May 31, 2003·The American Journal of Dermatopathology·Aldo González-Serva, George Kroumpouzos
Apr 6, 1987·FEBS Letters·C P SchellingC W Heizmann
Mar 1, 1983·International Journal of Dermatology·J H Pavlovitch, C Delescluse
Oct 1, 1983·The British Journal of Dermatology·Y MerotJ H Saurat
Jan 1, 1983·The American Journal of Physiology·J H PavlovitchJ H Saurat
Sep 1, 1986·The American Journal of Physiology·M RizkJ H Pavlovitch
Oct 1, 1986·The Journal of Investigative Dermatology·P Hawley-NelsonS H Yuspa
Feb 1, 1986·The Journal of Investigative Dermatology·P Hawley-NelsonS H Yuspa
Jun 1, 1986·The Journal of Investigative Dermatology·H KatayamaK Adachi
Feb 1, 1982·Journal of the American Academy of Dermatology·C M Lapiere
Aug 30, 1984·Biochemical and Biophysical Research Communications·M RizkS Balsan

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