Skin dose differences between intensity-modulated radiation therapy and volumetric-modulated arc therapy and between boost and integrated treatment regimens for treating head and neck and other cancer sites in patients

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
Gregory P Penoncello, George X Ding

Abstract

The purpose of this study was (1) to evaluate dose to skin between volumetric-modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT) treatment techniques for target sites in the head and neck, pelvis, and brain and (2) to determine if the treatment dose and fractionation regimen affect the skin dose between traditional sequential boost and integrated boost regimens for patients with head and neck cancer. A total of 19 patients and 48 plans were evaluated. The Eclipse (v11) treatment planning system was used to plan therapy in 9 patients with head and neck cancer, 5 patients with prostate cancer, and 5 patients with brain cancer with VMAT and static-field IMRT. The mean skin dose and the maximum dose to a contiguous volume of 2cm(3) for head and neck plans and brain plans and a contiguous volume of 5cm(3) for pelvis plans were compared for each treatment technique. Of the 9 patients with head and neck cancer, 3 underwent an integrated boost regimen. One integrated boost plan was replanned with IMRT and VMAT using a traditional boost regimen. For target sites located in the head and neck, VMAT reduced the mean dose and contiguous hot spot most noticeably in the shoulder region by 5.6% and 5.4%, respectively...Continue Reading

References

Dec 24, 2005·Medical Physics·Guowei ZhangCedric Yu
Jun 23, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Vanessa PanettieriIngmar Lax
Feb 16, 2013·Radiology and Oncology·Magdalena Peszynska-PiorunWojciech Golusinski
Jan 1, 2012·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·S A Syam KumarPadmanaban Sriram
Jan 1, 2012·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Wojciech LeszczyńskiMarta Szlag

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Citations

Oct 27, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Sara C ErridgeAlison L Stillie
Feb 8, 2018·Journal of Applied Clinical Medical Physics·Lilie WangGeorge X Ding
Aug 3, 2017·Journal of Applied Clinical Medical Physics·Kimberley LeggeJoerg Lehmann
Sep 27, 2018·Journal of Applied Clinical Medical Physics·Carlos FerrerEva Corredoira
Oct 23, 2018·Technology in Cancer Research & Treatment·Xiongfei LiaoLucia Clara Orlandini

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