Skin exposure to aliphatic polyisocyanates in the auto body repair and refinishing industry: II. A quantitative assessment

The Annals of Occupational Hygiene
Dhimiter BelloYoucheng Liu

Abstract

Skin exposure to isocyanates, in addition to respiratory exposures, may contribute to sensitization and asthma. Quantitative skin exposure data are scarce and quantitative methods limited. As part of the Survey of Painters and Repairers of Autobodies by Yale study, a method to sample and quantify human isocyanate skin exposure was developed (based on NIOSH 5525 method) and used to evaluate aliphatic isocyanate skin exposure in 81 auto body shop painters and body technicians. Wipe samples were collected from unprotected skin and from under PPE (gloves, clothing and respirator) using a polypropylene glycol-impregnated wipe. Hexamethylene diisocyanate (HDI), its polyisocyanates [HDI-derived polyisocyanates (pHDI)], isophorone diisocyanate (IPDI) and its polyisocyanates and IPDI-derived polyisocyanates (pIPDI) were quantified separately and also expressed as the total free isocyanate groups (total NCO). For unprotected skin areas, 49 samples were collected for spray painting, 13 for mixing, 27 for paint-related tasks (e.g. sanding and compounding) and 53 for non-paint-related tasks. Forty-three samples were also collected under PPE. The geometric mean (GM) [geometric standard deviation (GSD)] total NCO concentrations (ng NCO cm(-2)...Continue Reading

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May 3, 2007·Journal of Occupational and Environmental Hygiene·Dhimiter BelloYoucheng Liu
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Citations

May 30, 2009·Journal of the American Society for Mass Spectrometry·Justin M HettickPaul D Siegel
Aug 29, 2013·Journal of Toxicology and Environmental Health. Part a·Joachim D Pleil, Jon R Sobus
Aug 13, 2011·Journal of Occupational and Environmental Hygiene·Zeyede K ZelekeMagne Bråtveit
Aug 13, 2011·Journal of Occupational and Environmental Hygiene·Diana M CeballosCarolyn K Reeb-Whitaker
Nov 15, 2011·Journal of Occupational and Environmental Hygiene·Jennifer M ThomasenLeena A Nylander-French
Oct 17, 2012·Journal of Occupational and Environmental Hygiene·Thomas T De VriesCarrie A Redlich
Oct 15, 2013·Journal of Occupational and Environmental Hygiene·Carolyn Reeb-WhitakerDavid K Bonauto
Jul 29, 2009·The Annals of Occupational Hygiene·Kenneth W FentLeena A Nylander-French
Dec 24, 2010·The Annals of Occupational Hygiene·Diana M CeballosRussell Dills
Mar 28, 2012·The Annals of Occupational Hygiene·Adam V WisnewskiCarrie A Redlich
Aug 10, 2011·Occupational Medicine·G BielerB Danuser
Apr 30, 2010·Proceedings of the American Thoracic Society·Carrie A Redlich
Dec 25, 2013·The Annals of Occupational Hygiene·Diana M CeballosMichael G Yost
May 7, 2014·Toxicological Sciences : an Official Journal of the Society of Toxicology·Ajay P NayakDonald H Beezhold
Nov 13, 2013·Journal of Occupational and Environmental Hygiene·Diana CeballosMichael Yost
Nov 4, 2016·Journal of Occupational and Environmental Hygiene·Chun-Yip HonVictoria H Arrandale
Oct 4, 2016·The Annals of Occupational Hygiene·Homero HarariCarrie Redlich
Feb 2, 2012·Journal of Environmental Monitoring : JEM·Jennifer M Thomasen, Leena A Nylander-French

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