Skin function and skin disorders in Parkinson's disease

Journal of Neural Transmission
M FischerP A Fischer

Abstract

Cutaneous symptoms (seborrhoea and hyperhidrosis) in Parkinson's disease were investigated. In 70 treated patients with Parkinson's disease and 22 control subjects, non-invasive bioengineering methods (sebumetry, corneometry, pH) were carried out on the forehead, sternum and forearm. In addition, concomitant dermatoses and medication were recorded. 18.6% of the patients had seborrhoea on the forehead (>220 microg/cm2), 51.4% showed normal sebum values (100-220 microg/cm2) and 30% a sebostasis (<100 microg/cm2). Males has significantly higher sebum values than females. No relationship between the seborrhoea and the therapy for Morbus Parkinson was found. Patients with hyperhidrosis (n = 36) had significantly lower pH values (p < 0.05) on the forehead than those without hyperhidrosis. 22 patients (31.9%) reported a cold/hot flush and a further 13 (18.8%) had clinical rosacea. Seborrhoea is rare in treated Parkinsonian patients but hyperhidrosis is frequently found. Furthermore, a particular lack of vasostability (flush) appears to be an autonomic dysregulation in the skin related to Morbus Parkinson, which has not been studied to any extent to date.

References

Aug 1, 1991·Clinical Neuropharmacology·B Gomez-MancillaP J Bédard
May 1, 1989·The British Journal of Dermatology·M J LevellW J Cunliffe
Jul 1, 1989·Acta Neurologica Scandinavica·J C Villares, E A Carlini
Jul 4, 1970·Lancet·J L Burton, S Shuster
Mar 1, 1973·The British Journal of Dermatology·J L BurtonS Shuster
Mar 1, 1973·The Journal of Investigative Dermatology·S R KohnW H Timberlake
Aug 1, 1995·The British Journal of Dermatology·S WaltonR A Reese
Oct 1, 1994·Journal of Neurology·Y ManoR F Mayer
Jan 1, 1996·The Journal of Investigative Dermatology·M Wintzen, B A Gilchrest
Apr 1, 1997·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·O I KolevL Tibbling
Jan 1, 1997·Journal of Neural Transmission·E MartignoniG Nappi
Jan 1, 1962·The Journal of Investigative Dermatology·P E POCHIH MESCON

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Citations

Apr 6, 2002·Expert Opinion on Pharmacotherapy·Thomas Müller
Mar 24, 2005·Postgraduate Medicine·Farah Rukhsana Abdulla, Robert T Brodell
Apr 12, 2015·Practical Neurology·Ralph Gregory, Sarah Miller
Feb 5, 2016·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C DahmsS Rupprecht
Oct 13, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·R J MathieuB Nardone
Jul 25, 2019·Revista da Associação Médica Brasileira·Isadora AntunesThereza Cristina d'Ávila Winckler
Sep 25, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Martine VisserJacobus J Van Hilten
Nov 30, 2006·Journal of Neurology·Masaaki Hirayama
Feb 14, 2008·Stereotactic and Functional Neurosurgery·Esteban PeñaRafael G Sola
May 26, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·A-H R JørgensenJ P Thyssen
Dec 24, 2018·BMJ : British Medical Journal·Christina George, Sarah Walsh
Sep 8, 2016·Movement Disorders Clinical Practice·Matej Skorvanek, Kailash P Bhatia
Jul 12, 2020·Journal of Clinical Medicine·Rosalind M TuckerR John Dobbs
Jul 13, 2016·Journal of Neurochemistry·Sigurlaug Sveinbjornsdottir
Jan 1, 2015·International Scholarly Research Notices·Anthony KarpouzisStavroula Veletza
Mar 28, 2018·Experimental Dermatology·Ewan A LanganRalf Paus
Jun 24, 2017·CNS Drugs·Eva Schaeffer, Daniela Berg
Nov 29, 2020·Parkinsonism & Related Disorders·Nicki NiemannJoseph Jankovic
Dec 23, 2019·Clinics in Dermatology·Uwe Wollina
Feb 8, 2021·Parkinsonism & Related Disorders·Deepika DineshNatalia Palacios

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