Skin microbiota and human 3D skin models

Experimental Dermatology
Franziska RademacherJürgen Harder

Abstract

Although the role of the microbiota in skin homeostasis is still emerging, there is growing evidence that an intact microbiota supports the skin barrier. The increasing number of research efforts that are trying to shed more light on the human skin-microbiota interaction requires the use of suitable experimental models. Three-dimensional (3D) skin equivalents have been established as a valuable tool in dermatological research because they contain a fully differentiated epidermal barrier that reflects the morphological and molecular characteristics of normal human epidermis. In this review, we provide an overview of current 3D skin models and illustrate the potential of 3D skin models to study the human skin-microbiota interplay.

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Citations

Jul 1, 2020·Advanced Materials·Rezvan JamaledinPooyan Makvandi
Jul 22, 2020·Critical Reviews in Microbiology·Diletta Francesca SquarzantiBarbara Azzimonti
Aug 5, 2020·Experimental Dermatology·Hila EmmertJürgen Harder
Sep 15, 2020·Journal of Oral Microbiology·Sophie E MountcastleSarah A Kuehne
Jul 9, 2020·Frontiers in Medicine·Alice RouanetMagali Cordaillat-Simmons
Nov 1, 2020·Journal of Exposure Science & Environmental Epidemiology·Benedetta PetraccaMarc Eeman
Jun 1, 2021·Microbiome·Manon BoxbergerBernard La Scola
Aug 14, 2021·Experimental Dermatology·Harri AleniusStephan Weidinger

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