Skin prick testing in atopic eczema: atopic to what and at what age?

World Journal of Pediatrics : WJP
Kam Lun HonTing Fan Leung

Abstract

Atopic eczema is a common and distressing disease. This study aimed to review the age-dependent pattern of atopic sensitization to food and aeroallergens in patients with eczema by skin prick testing. The results of skin prick test (SPT), serum IgE, bronchial challenge test, and family history of atopy in eczema patients seen at a pediatric dermatology clinic were reviewed. SPT results were available in 816 eczema patients. In these patients, 90% had atopic sensitization to at least one aeroallergen, 69% to at least one food allergen, and 94% to at least one allergen by SPT. Together with a family history of atopy in parents or siblings and a personal history of airway atopies, 97% and 99.8% of the patients were atopic, respectively. Bronchial hyper-reactivity (BHR) was demonstrated in 44% of 339 patients. Aeroallergen was more prevalent than food allergen sensitization among children older than 10 years. The mites (D. pteronysissnus, D. farinae and Blomia Tropicalis) were the most prevalent allergens regardless of age and BHR, but D. pteronysissnus and D. farinae sensitization were more prevalent among BHR-positive patients. Beef is the least sensitized food protein in all ages. The majority of patients with eczema are atopic ...Continue Reading

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Citations

Oct 3, 2014·Pediatric Allergy, Immunology, and Pulmonology·Elham HossnyNahla Abdul-Rahman
Dec 20, 2015·World Journal of Pediatrics : WJP·Kam Lun HonTing-Fan Leung
Jun 15, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Chantel NgChun Kwok Wong
May 28, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·E McManusN J Levell
Dec 8, 2019·Occupational Medicine·Paul J Nicholson

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