SLE or hypothyroidism: who can triumph in cardiac tamponade?

BMJ Case Reports
Sameer Sadashiv ChaudhariSavi Mushiyev

Abstract

A 36-year-old Hispanic woman with a history of systemic lupus erythaematosus (SLE) in remission presented with progressive dyspnoea, bilateral leg swelling and increasing fatigue with rapid weight gain over the past few months. Her physical examination showed mildly tender thyromegaly and pericardial rub. Investigations showed new onset marked hypothyroidism as well as an active lupus serology with echocardiogram confirming severe pericardial effusion and a tamponade phenomenon. Urgent pericardiocentesis relieved her acute symptoms, and prompt treatment with thyroxine replacement and immunosuppression for lupus disease was initiated. Pericardial fluid analysis remained negative for any malignancy and/or infection/s. The patient had a gradual and consistent improvement with this treatment. She was discharged and appeared to be clinically stable at subsequent follow-up visits. However, the case remained a diagnostic dilemma over whether the tamponade was being driven by hypothyroidism versus lupus, leaving us with an opportunity to explore further.

References

Nov 1, 1976·The American Journal of the Medical Sciences·E N SmolarA C Carter
Dec 1, 1990·American Heart Journal·U M Kabadi, S P Kumar
Sep 1, 1972·American Journal of Diseases of Children·R J Lerer
Oct 1, 1983·Archives of Internal Medicine·S Arvan
Oct 1, 1980·Clinical Endocrinology·C A HardistyD S Munro
Aug 1, 1993·The American Journal of Medicine·G R CoreyT C Wall
Feb 24, 2001·Australian and New Zealand Journal of Medicine·N SharmaS Varma
Aug 21, 2002·Arquivos brasileiros de cardiologia·Acir RachidRafael P Hagemann
Jun 27, 2003·Japanese Heart Journal·Chih-Ta LinChih-Lon Lin
Apr 1, 1965·Radiology·R S KURTZMANJ J CHEPEY
Dec 10, 2003·Medicine·Pierre-Yves LevyDidier Raoult
May 4, 2004·European Heart Journal·Bernhard MaischUNKNOWN Task Force on the Diagnosis and Management of Pricardial Diseases of the European Society of Cardiology
Jul 12, 2005·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Andrew K KaruJohn VanderWoude
Dec 21, 2006·Herz·Petar M SeferovićBernhard Maisch
May 5, 2007·The American Journal of Cardiology·Shomron Ben-HorinAvi Livneh
May 29, 2008·Arquivos brasileiros de endocrinologia e metabologia·Daniela P P Oliveira ViggianoVitalina de Souza Barbosa
Dec 17, 2009·Metabolism: Clinical and Experimental·Alessandro AntonelliStefano Bombardieri
Jul 6, 2010·The American Journal of the Medical Sciences·Jian-Liung WangKuo-Chun Hung
Jul 27, 2010·Rheumatology International·Kundan KumarAlakendu Ghosh
Feb 3, 2011·Journal of Pediatric Endocrinology & Metabolism : JPEM·Tania Martinez-SotoJosephine Ho
Jan 27, 2012·The Journal of Clinical Hypertension·Joel Handler
Jul 28, 2012·Indian Journal of Endocrinology and Metabolism·Rudrajit PaulGouranga Santra
Sep 25, 2012·BMJ Case Reports·Mariam Toufic ArabiMohamad Hassan Itani
Feb 8, 2013·BMJ Case Reports·Ashvin ButalaAlan Sacerdote
Jul 23, 2013·BMJ Case Reports·Wilson ChengParesh Mistry
Aug 14, 2013·Pediatrics International : Official Journal of the Japan Pediatric Society·Erkut OzturkEnder Odemis
Nov 26, 2013·Rheumatic Diseases Clinics of North America·Jonathan J Miner, Alfred H J Kim
Dec 24, 2013·The American Journal of Emergency Medicine·Meera EkkaNayer Jamshed
Dec 26, 2013·QJM : Monthly Journal of the Association of Physicians·R Abdallah, S Atar
Jan 1, 2014·The Canadian Journal of Cardiology·David T HarnettSean F Hamilton
May 31, 2014·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Wen-Ya LinHeng-Kuei Lin

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