Sleep apnea in children with laryngomalacia: diagnosis via sedated endoscopy and objective outcomes after supraglottoplasty

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
G Paul DigoyJulie Stoner

Abstract

The authors study the contribution of laryngomalacia to obstructive sleep apnea syndrome (OSAS) in children older than 12 months. The clinical and polysomnographic outcomes in patients with OSAS who underwent a supraglottoplasty were also studied. Tertiary care children's hospital. A case series with chart review. A review of consecutive pediatric patients diagnosed with both OSAS and state-dependant laryngomalacia (SDL) between 2005 and 2008. The diagnosis of SDL was made via laryngoscopy under light general anesthesia (sleep endoscopy). All subjects underwent a supraglottoplasty. A total of 43 patients met inclusion criteria, and 36 patients had complete pre- and postoperative data available for review. The apnea-hypopnea index (AHI) score decreased following supraglottoplasty for 33 (92%; 95% confidence interval [CI], 78%-98%) of the 36 patients. The mean (SD) change in AHI score (calculated as the postoperative minus the preoperative measure) was -9.2 (11.2), representing a statistically significant reduction (95% CI, -13.0 to -5.5; P < .0001). The mean (SD) preoperative AHI was 13.3 (12.9). The minimum oxygen saturation increased following supraglottoplasty for 21 (58%; 95% CI, 41%-74%). The mean (SD) change in the minimum...Continue Reading

References

Dec 31, 1997·The Annals of Otology, Rhinology, and Laryngology·M R Amin, G Isaacson
Mar 11, 2005·The Annals of Otology, Rhinology, and Laryngology·Joseph L SmithAnthony Mortelliti
May 12, 2005·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Ron B Mitchell, James Kelly
Jun 16, 2005·Pediatric Pulmonology·Shmuel GoldbergEitan Kerem
May 17, 2006·Archives of Otolaryngology--head & Neck Surgery·Fabiana Cardoso Pereira ValeraDaniel S Küpper
Dec 2, 2006·The Journal of Pediatrics·Riva TaumanDavid Gozal
Jun 30, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Ron B Mitchell, James Kelly
Jan 23, 2008·Archives of Otolaryngology--head & Neck Surgery·Gresham T RichterDana M Thompson
Jul 22, 2008·The Laryngoscope·Mark E ZafereoKevin D Pereira
Apr 16, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Alekos D TsamaloukasHeiko Heerklotz
Jun 16, 2009·International Journal of Pediatric Otorhinolaryngology·Tony E O'ConnorShyan Vijayasekaran
Aug 20, 2009·Anesthesia and Analgesia·Mohamed MahmoudSenthilkumar Sadhasivam
Jun 23, 2010·The Laryngoscope·Mahilravi ThevasagayamHamdy El-Hakim
Sep 24, 2010·The Annals of Otology, Rhinology, and Laryngology·Jin YeYuan Li
Dec 1, 2010·International Journal of Pediatric Otorhinolaryngology·Sally M Revell, William D Clark

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Citations

Sep 26, 2014·Current Opinion in Otolaryngology & Head and Neck Surgery·G Paul Digoy, Scott D Burge
May 13, 2014·International Journal of Pediatric Otorhinolaryngology·Frank G Garritano, Michele M Carr
Aug 3, 2013·Pediatric Clinics of North America·Nathan S Alexander, James W Schroeder
Jan 18, 2016·Pediatric Neurology·Nataliya TkachenkoSanjeev Kothare
Aug 12, 2014·Acta otorrinolaringológica española·Eduard Esteller
Jan 22, 2013·International Journal of Pediatric Otorhinolaryngology·José Antonio PintoRodrigo Prestes dos Reis
Aug 6, 2013·International Journal of Pediatric Otorhinolaryngology·Karin P Q Oomen, Vikash K Modi
Feb 24, 2015·International Journal of Pediatric Otorhinolaryngology·Caitlin A MaseSanjay R Parikh
Jul 3, 2016·International Journal of Pediatric Otorhinolaryngology·Chia-Fan LeeKun-Tai Kang
Jun 18, 2016·The Laryngoscope·Norman R FriedmanDylan K Chan
Dec 9, 2016·International Anesthesiology Clinics·Ngoc Nguyen-Famulare, Michel Nassar
Nov 8, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Shan HeStacey L Ishman
Jun 16, 2016·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·John P DahlSanjay R Parikh
Jan 5, 2017·Pediatric Pulmonology·A BoudewynsS L Verhulst
Jun 12, 2019·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michael P AvillionMacario Camacho
Dec 10, 2020·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Woranart RatanakornNarong Simakajornboon
Jul 10, 2017·International Journal of Pediatric Otorhinolaryngology·Timothy CooperHamdy El-Hakim

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Methods Mentioned

BETA
sedation

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