Sleep Apnea in Moderate-Severe Obese Patients

Sleep & Breathing = Schlaf & Atmung
Marghertia SergiDario Comi

Abstract

Obesity induces multiple physiologic changes at the respiratory and circulatory systems level. A study was developed to identify symptoms and signs able to discriminate subjects at high risk of obstructive sleep apnea (OSA) and to evaluate the presence of OSA in a population of obese patients referred to the Clinical Nutrition Service of the Luigi Sacco Hospital for weight loss therapy. Twenty-seven obese patients (14 males, 13 females) without neurologic, cardiac, and lung diseases were measured for height, weight, neck, waist, and hip circumference; a sample of venous blood was taken for hematological data; and were given a pulmonary function test, hemogasanalysis, and full-night polysomnography. Statistical analysis were performed using paired and unpaired StudentOs t test, PearsonOs chi square, and Spearmann Rank correlation; the significance level was set at p<0.05. The results showed hemotological values in the normal range and pulmonary function findings were not different from predicted, but expiratory reserve volume (ERV), as expected in obese subjects, was significantly reduced (p<0.001). Waist, hip, and neck circumference, and waist/hip ratio were 114 +/-14, 118 +/-12, 44 +/-4, and 0.96 +/-0.4 cm respectively. An apn...Continue Reading

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Citations

Apr 25, 2012·Sleep & Breathing = Schlaf & Atmung·Katherine M SharkeyRichard P Millman
Sep 20, 2011·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Jason J RasmussenMohamed R Ali
Jun 16, 2010·Internal Medicine Journal·M Soriano-CoP A McCullough
Oct 29, 2020·Journal of Family Medicine and Primary Care·Prashant KumarM S Kanwar

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