Sleep apnea in patients with oral cavity and oropharyngeal cancer after surgery and chemoradiation therapy

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Wei QianKevin M Higgins

Abstract

To determine the point prevalence of sleep apnea in patients following oral and oropharyngeal cancer treatment at a major tertiary care referral center. A retrospective cross-sectional survey. Twenty-four patients with established oral or oropharyngeal cancer were submitted to overnight polysomnography. The surgical group consisted of 15 patients (11 male, 4 female; average age 64.2 yrs) having undergone primary surgery with radial forearm free flap reconstruction. The remaining patients (5 male, 4 female; average age 54.8 yrs) were treated nonsurgically with chemoradiation therapy. The fatigue-related daytime sleepiness was measured with the Epworth sleepiness scale (ESS). Eleven patients in the surgical group and three in the nonsurgical group had a respiratory disturbance index (RDI) greater than 15 (odds ratio = 5.5, P = 0.092). Twelve patients in the surgical group and five in the nonsurgical group had significant oxygen desaturation during sleep hours (odds ratio = 3.3, P = 0.356). There was no observed significant correlation between RDI and oxygen desaturation (r(2) = 0.28), nor was there any observed association between the RDI and ESS score (r(2) = 0.18). This preliminary study has suggested that surgical patients in ...Continue Reading

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Citations

Apr 26, 2014·American Journal of Clinical Oncology·Jessica Zhou, Shruti Jolly
Oct 19, 2016·Journal of Maxillofacial and Oral Surgery·Ottavio PiccinFrancesca Milano
Mar 24, 2017·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·A LothN Fakhry
Feb 3, 2016·Head & Neck·Alejandro MazarroCoro Bescós
Apr 26, 2019·The Laryngoscope·Oren FactorRichard L Bakst
Jun 5, 2019·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Lei OuyangShisheng Li
Jan 1, 2016·Cancers of the Head & Neck·Carolyn Y Fang, Carolyn J Heckman
May 26, 2017·The Laryngoscope·Phillip HuyettRyan J Soose
Jul 28, 2019·Sleep Medicine Reviews·Angelina M M SantosoIrma M Verdonck-de Leeuw
Feb 10, 2021·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Ronald GavidiaRonald D Chervin

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Methods Mentioned

BETA
surgical resection
dissection

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