Sleep attacks and dopamine agonists for Parkinson's disease: what is currently known?

CNS Drugs
Theresa A Zesiewicz, Robert A Hauser

Abstract

The aetiology of sleep disturbances in patients with Parkinson's disease is multifactorial. Medications, the disease process and underlying sleep disorders may contribute to sleepiness in patients with the disease. Somnolence, excessive daytime sleepiness and sleep attacks appear to be more common in patients with Parkinson's disease who are treated with dopamine receptor agonists than in those who are treated with other antiparkinsonian agents, although virtually all dopaminergic antiparkinsonian medications may contribute to sleepiness. Somnolence caused by dopamine agonists may be dose related and occurs most frequently during the dose-escalation phase. Somnolence may also emerge or worsen after a period of time on a stable dose. Patients with Parkinson's disease and caregivers should be informed about the risk of sleepiness and sleep attacks associated with dopaminergic medications and the potential implications for driving safety.

References

Jan 1, 1990·Movement Disorders : Official Journal of the Movement Disorder Society·S A FactorW J Weiner
Dec 1, 1988·Clinical Neuropharmacology·A J LeesV L Campbell
Dec 10, 1999·Movement Disorders : Official Journal of the Movement Disorder Society·E TandbergK Karlsen
Apr 7, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·C W OlanowT Roth
Apr 25, 2000·Lancet·A H Schapira
Apr 25, 2000·Lancet·J J FerreiraO Rascol
Jun 15, 2000·Pharmacotherapy·M RyanA Wells
Jun 17, 2000·Movement Disorders : Official Journal of the Movement Disorder Society
Aug 6, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·S J FruchtS Fahn
Aug 6, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·R A HauserT A Zesiewicz
Oct 18, 2000·JAMA : the Journal of the American Medical Association·UNKNOWN Parkinson Study Group
Feb 24, 2001·Movement Disorders : Official Journal of the Movement Disorder Society·G M Wali
May 10, 2001·Parkinsonism & Related Disorders·C C. SanjivD B. Calne
May 10, 2001·Parkinsonism & Related Disorders·A RabinsteinW J. Weiner
Jun 8, 2001·Movement Disorders : Official Journal of the Movement Disorder Society·F Tracik, G Ebersbach
Oct 23, 2001·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·M EtminanP A Rochon
Feb 2, 2002·JAMA : the Journal of the American Medical Association·Douglas E HobsonJonathan Fleming
Jul 2, 2008·Parkinsonism & Related Disorders·P K PalJ A Fleming

❮ Previous
Next ❯

Citations

Mar 2, 2005·Sleep Medicine Reviews·Sabine Gautier-SauvignéRaymond Cespuglio
Aug 21, 2012·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M LouterS Overeem
Feb 18, 2011·CNS Drugs·Bettina KnieK Ray Chaudhuri
Jun 2, 2011·The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists·Pamela ForalMark Malesker
Jul 28, 2016·Expert Review of Neurotherapeutics·F Javier Álvarez
Mar 7, 2017·Frontiers in Neurology·Giuseppe LoddoFederica Provini
May 7, 2020·Journal of Neurology, Neurosurgery, and Psychiatry·Stefanie Theresa JostUNKNOWN EUROPAR and the International Parkinson and Movement Disorders Society Non-Motor Parkinson's Disease Study Group.
Feb 2, 2021·Expert Review of Neurotherapeutics·Katarina RukavinaK Ray Chaudhuri

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Drug Safety : an International Journal of Medical Toxicology and Drug Experience
K Ray ChaudhuriChristine Brefel-Courbon
Movement Disorders : Official Journal of the Movement Disorder Society
Yvonne KörnerH P Krüger
Parkinsonism & Related Disorders
F StocchiDEEP study group
© 2022 Meta ULC. All rights reserved