Sleep-disordered breathing in children with Chiari malformation type II and myelomeningocele

Pediatrics International : Official Journal of the Japan Pediatric Society
Muslim M AlsaadiDavid Gozal

Abstract

The prevalence of sleep-disordered breathing (SDB) in children with Chiari malformation type II (CM-II), a known association of neural tube defects (NTD), has not been well documented. The aim of the present study was to assess the prevalence and possible predictive factors of SDB in patients with CM-II. The study included all patients with documented CM-II who were routinely referred from the Neurosurgery Clinic to the University Sleep Disorders Centre at King Khalid University Hospital, Riyadh, Saudi Arabia, between January 2002 and July 2009. Overnight full polysomnography (PSG) was performed in all patients. Polysomnographic data were analyzed using descriptive statistics. Sixteen children (11 boys, five girls) were included in the study; their mean age was 4.7 years (range, 0.8-10 years) and their mean body mass index was 18.05 kg/m(2) (range, 15.4-25.4 kg/m(2) ). For the whole group, the mean apnea-hypopnea index (AHI) was 6.3/h (range, 0.2-24.5/h), with AHI recorded as >5/h in five patients (31.3%) and ≥ 10/h in three patients (18.8%). The mean central apnea-hypopnea index was 5.9/h (range, 0-24.5/h) and the mean obstructive apnea-hypopnea index was 0.4/h (range, 0-2.9/h). The mean arousal index was 15.1/h (range, 5-34/h...Continue Reading

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Citations

Sep 10, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Martina Messing-Jünger, Andreas Röhrig
Mar 29, 2014·Sleep Medicine Clinics·Christopher Cielo, Carole L Marcus
Sep 4, 2015·European Radiology·Ramona WoitekGregor Kasprian
Apr 4, 2015·Journal of Neurosurgery. Pediatrics·Daxa M PatelJeffrey P Blount
Nov 7, 2015·The European Respiratory Journal·Athanasios G KaditisStijn Verhulst
Dec 9, 2017·The European Respiratory Journal·Athanasios G KaditisStijn Verhulst
Mar 19, 2019·Anesthesia Progress·Yoshiki ShionoyaKatsuhisa Sunada
Aug 20, 2019·Journal of Perinatology : Official Journal of the California Perinatal Association·Renée A Shellhaas
Jul 20, 2019·Journal of Perinatology : Official Journal of the California Perinatal Association·Ellen Bendel-StenzelAlicen B Spaulding
Jan 18, 2018·Topics in Spinal Cord Injury Rehabilitation·Shubhra Mukherjee, Jacqueline Pasulka
Dec 29, 2020·Neurosurgery·Brandon G RocqueJeffrey P Blount
Dec 10, 2017·The Journal of Pediatrics·Renée A ShellhaasRonald D Chervin

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