Sleep disorders and risk of dementia in patients with new-onset type 2 diabetes: A nationwide population-based cohort study.

Journal of Diabetes
Dallae Jin, Jae Woo Choi

Abstract

This study examined the relationship between sleep disorders and the risk of dementia in patients with newly diagnosed type 2 diabetes. This study used the Korean Health Screening Cohort data and included 39 135 subjects aged ≥40 years with new-onset type 2 diabetes between 2004 and 2007, with follow-up throughout 2013. Sleep disorders were measured by F51(sleep disorders not due to a substance or known physiological condition) or G47(sleep disorders) under International Classification of Diseases, Tenth Revision (ICD-10) codes as a primary diagnosis, and the adjusted hazard ratio (AHR) and 95% CI of all-cause dementia, Alzheimer disease, vascular dementia, and other dementia were estimated using multivariable Cox proportional hazards regression models. In the patients with type 2 diabetes with an age range between 42 and 84 years (M = 57.8, SD = 9.5), this study identified 2059 events of dementia during an average follow-up time of 5.7 years. In patients with type 2 diabetes, subjects with sleep disorders were associated with an increased risk of all-cause dementia (AHR, 1.46; 95% CI, 1.19-1.80), Alzheimer disease (AHR, 1.39; 95% CI, 1.02-1.88), and other dementia (AHR, 1.69; 95% CI, 1.23-2.31) compared to those without sleep ...Continue Reading

References

Sep 10, 2002·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Dharam P Agarwal
Jan 18, 2003·Sleep Medicine Reviews·Maurice M Ohayon
Jul 20, 2010·International Journal of Stroke : Official Journal of the International Stroke Society·Alberto Ramos-SepulvedaTatjana Rundek
Aug 3, 2010·Journal of Epidemiology and Community Health·Peter C ElwoodJohn E J Gallacher
Jun 4, 2011·Sleep Medicine Reviews·Emilie Fortier-BrochuCharles M Morin
Mar 1, 2012·Diabetes & Metabolism Journal·Amarabalan RajendranMohamed Shuaib
Oct 23, 2013·JAMA Neurology·Adam P SpiraSusan M Resnick
May 21, 2014·Journal of Diabetes Investigation·Kapil GudalaAnil Bhansali
Jun 10, 2014·Neurobiology of Aging·Brendan P Lucey, Randall J Bateman
Nov 14, 2014·Journal of Alzheimer's Disease : JAD·Diana WuchererWolfgang Hoffmann
Dec 3, 2014·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Christian BenedictHelgi B Schiöth
Mar 3, 2015·Lancet Neurology·Paula S KoekkoekGeert Jan Biessels
Mar 22, 2015·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Kristine YaffeAmy Byers
May 8, 2015·Neurochemical Research·Nadia Aalling JessenMaiken Nedergaard
Jun 11, 2015·Neurobiology of Aging·Kate E SprecherRuth M Benca
Oct 16, 2015·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Eus J W Van SomerenMichael W L Chee
Feb 8, 2018·Metabolism: Clinical and Experimental·Calliope HolingueAdam P Spira
Oct 26, 2018·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·O GroeneveldUNKNOWN COG-ID study group
Feb 2, 2019·Aging and Disease·Tseng Chin-Hsiao
Aug 29, 2019·Epidemiology and Psychiatric Sciences·I K Wium-AndersenM K Wium-Andersen
Nov 14, 2019·Diabetes Care·Annelies BrouwerMarijke A Bremmer
Dec 28, 2019·Journal of Neurology, Neurosurgery, and Psychiatry·Wei XuLan Tan
Mar 25, 2020·Journal of Pharmaceutical Health Care and Sciences·Yuuki AkagiMakoto Ujihara

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.