Sleep During Menopausal Transition: A 6-Year Follow-Up

Sleep
Laura LampioTarja Saaresranta

Abstract

Menopausal transition is associated with increased dissatisfaction with sleep, but the effects on sleep architecture are conflicting. This prospective 6-year follow-up study was designed to evaluate the changes in sleep stages and sleep continuity that occur in women during menopausal transition. Sixty women (mean age 46.0 years, SD 0.9) participated. All women were premenopausal at baseline, and at the 6-year follow-up, women were in different stages of menopausal transition. Polysomnography was used to study sleep architecture at baseline and follow-up. The effects of aging and menopause (assessed as change in serum follicle-stimulating hormone [S-FSH]) on sleep architecture were evaluated using linear regression models. After controlling for body mass index, vasomotor, and depressive symptoms, aging of 6 years resulted in shorter total sleep time (B -37.4, 95% confidence interval [CI] -71.5 to (-3.3)), lower sleep efficiency (B -6.5, 95%CI -12.7 to (-0.2)), as well as in increased transitions from slow-wave sleep (SWS) to wakefulness (B 1.0, 95%CI 0.1 to 1.9), wake after sleep onset (B 37.7, 95%CI 12.5 to 63.0), awakenings per hour (B 1.8, 95%CI 0.8 to 2.8), and arousal index (B 2.3, 95%CI 0.1 to 4.4). Higher S-FSH concentra...Continue Reading

References

Jan 1, 1985·Electroencephalography and Clinical Neurophysiology·J A Horne, V J Moore
Jan 1, 1966·Psychophysiology·H W AgnewR L Williams
Sep 1, 1994·Sleep·S Woodward, R R Freedman
Jan 1, 1994·American Journal of Epidemiology·R LuotoA Uutela
Jan 1, 1997·Experimental Aging Research·K B Pandolf
Jul 20, 2001·Journal of Psychiatric Research·O Le BonP Linkowski
Mar 5, 2003·American Journal of Respiratory and Critical Care Medicine·Terry YoungAndrea Peterson
Jun 1, 1961·Archives of General Psychiatry·A T BECKJ ERBAUGH
May 29, 2004·Journal of Pain and Symptom Management·Josée SavardCharles M Morin
Jul 9, 2004·Fertility and Sterility·Robert R Freedman, Timothy A Roehrs
Dec 17, 2004·Behavioral Sleep Medicine·Katherine M SharkeyMary A Carskadon
Jan 18, 2006·The American Journal of Medicine·Robert R Freedman
Jul 14, 2006·Menopause : the Journal of the North American Menopause Society·Robert R Freedman, Timothy A Roehrs
Nov 9, 2006·Acta Obstetricia Et Gynecologica Scandinavica·Ulla AnttalainenOlli Polo
May 9, 2007·Menopause : the Journal of the North American Menopause Society·Robert R Freedman, Timothy A Roehrs
Mar 4, 2008·Lancet·Heidi D Nelson
Jun 20, 2008·Menopause : the Journal of the North American Menopause Society·Pauline M MakiStacie E Geller
May 6, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Helena HachulEdmund Chada Baracat
Jun 24, 2009·Menopause : the Journal of the North American Menopause Society·Janneke Berecki-GisolfAnnette J Dobson
Sep 17, 2010·Seminars in Reproductive Medicine·Hadine JoffeKatherine M Sharkey
Feb 8, 2011·Maturitas·Päivi Polo-Kantola
Feb 22, 2012·The Journal of Clinical Endocrinology and Metabolism·Siobán D HarlowUNKNOWN STRAW + 10 Collaborative Group
Mar 15, 2012·Menopause : the Journal of the North American Menopause Society·Rebecca C ThurstonKaren A Matthews
Sep 26, 2013·Menopause : the Journal of the North American Menopause Society·Elena ToffolPäivi Polo-Kantola
Apr 24, 2014·Menopause : the Journal of the North American Menopause Society·Laura LampioTarja Saaresranta
Jun 18, 2014·BMC Psychiatry·Elena ToffolPäivi Polo-Kantola
Sep 27, 2014·Fertility and Sterility·Massimiliano de ZambottiFiona C Baker
Feb 3, 2015·The Journal of Clinical Endocrinology and Metabolism·Massimiliano de ZambottiFiona C Baker
Jul 5, 2015·Psychoneuroendocrinology·Fiona C BakerMassimiliano de Zambotti
Jul 15, 2015·Menopause : the Journal of the North American Menopause Society·Joan L Shaver, Nancy F Woods
Oct 5, 2016·Behavioral Sleep Medicine·Irina VirtanenPäivi Polo-Kantola
Jan 18, 2017·Journal of Sleep Research·Johanna F A SchwarzJenny Theorell-Haglöw

❮ Previous
Next ❯

Citations

Apr 25, 2020·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Erica C JansenRuy López-Ridaura
Aug 1, 2020·Endocrinology·Alana M C Brown, Nicole J Gervais
Mar 29, 2020·Menopause : the Journal of the North American Menopause Society·Agnes L NeutzlingMaria Teresa A Olinto
Jun 7, 2019·Journal of Women's Health·Dana R Schreiber, Natalie D Dautovich
Mar 7, 2020·Journal of Psychosomatic Obstetrics and Gynaecology·Jelena DotlicTatjana Gazibara
Aug 3, 2020·Menopause : the Journal of the North American Menopause Society·Katherine M HatcherMegan M Mahoney
Oct 29, 2020·Menopause : the Journal of the North American Menopause Society·Katherine M HatcherMegan M Mahoney
Feb 13, 2021·Obstetrics and Gynecology Clinics of North America·Claudio N Soares, Alison K Shea
Mar 7, 2018·Menopause : the Journal of the North American Menopause Society·Riina KatainenPäivi Polo-Kantola
May 11, 2021·Frontiers in Neurology·Pamela Alebna, Nasim Maleki
Jun 8, 2021·Current Opinion in Endocrine and Metabolic Research·Kathleen Van DykJudith E Carroll
Dec 17, 2020·Sleep·Nea KalleinenTarja Saaresranta
Aug 7, 2021·Clinics in Chest Medicine·Lauren TobiasChristine H J Won

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.