Sleep, emotional distress, and physical health in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study

Psycho-oncology
Lauren C DanielKevin R Krull

Abstract

Sleep disorders are associated with psychological and physical health, although reports in long-term survivors of childhood cancer are limited. We characterized the prevalence and risk factors for behaviors consistent with sleep disorders in survivors and examined longitudinal associations with emotional distress and physical health outcomes. Survivors (n = 1933; median [IQR] age = 35 [30, 41]) and siblings (n = 380; age = 33 [27, 40]) from the Childhood Cancer Survivor Study completed measures of sleep quality, fatigue, and sleepiness. Emotional distress and physical health outcomes were assessed approximately 5 years before and after the sleep survey. Multivariable logistic or modified Poisson regression models examined associations with cancer diagnosis, treatment exposures, and emotional and physical health outcomes. Survivors were more likely to report poor sleep efficiency (30.8% vs 24.7%; prevalence ratio [PR] = 1.26; 95% confidence interval, 1.04-1.53), daytime sleepiness (18.7% vs 14.2%; PR = 1.31 [1.01-1.71]), and sleep supplement use (13.5% vs 8.3%; PR = 1.56 [1.09-2.22]) than siblings. Survivors who developed emotional distress were more likely to report poor sleep efficiency (PR = 1.70 [1.40-2.07]), restricted slee...Continue Reading

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Citations

Oct 28, 2019·Psycho-oncology·Lauren C DanielUNKNOWN International Psycho-Oncology Society Pediatrics Special Interest Group
Mar 4, 2020·The Cochrane Database of Systematic Reviews·Sylvia van DeurenJacqueline Loonen
Dec 4, 2019·Current Opinion in Pediatrics·Lori WienerAmanda L Thompson
Apr 13, 2020·Journal of Pediatric Psychology·Hyun KimKristin A Long
Jul 8, 2020·Brain Sciences·Maria Paola MogaveroRaffaele Ferri
Jan 4, 2021·Journal of Cancer Survivorship : Research and Practice·Ankie Tan CheungJoyce Oi Kwan Chung
Feb 16, 2021·Cephalalgia : an International Journal of Headache·Olafur B DavidssonThomas Folkmann Hansen
Apr 23, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Matthew C HockingHeather M Conklin
Apr 6, 2021·Pediatric Blood & Cancer·Samir PatelAnita Mahajan
Aug 27, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Margaret M LubasTara M Brinkman

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