PMID: 3769574Nov 1, 1986Paper

Sleep in Pierre Robin syndrome

Chest
S SpierT Egan

Abstract

Eight patients (aged 8 to 22 years) with the Pierre Robin syndrome underwent sleep studies. Seven demonstrated significant although minor degrees of increased sleep disturbances and apneas, and less time spent in the rapid-eye-movement (REM) stage of sleep. One patient who had previously undergone mandibular corrective surgery had major sleep abnormalities (central apnea index of 81.7 although an obstructive sleep apnea index of only 1.9). The patients had small mandibles, as demonstrated by lateral cephalometric roentgenography, and mildly increased right ventricular diastolic dimensions, as shown by M-mode echocardiography. Snoring was present in all of these patients and in 13 of 22 patients questioned from our Pierre Robin clinic. We conclude that minor abnormalities in sleep, mandibular size, and right ventricular size persist well into adolescence in the majority of patients with Pierre Robin syndrome. These appear to be clinically insignificant; however, a small percentage of such patients may continue to have major sleep disturbances.

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Citations

Dec 10, 2003·International Journal of Pediatric Otorhinolaryngology·L J Hans HoeveKoen F M Joosten
Oct 11, 2003·International Journal of Pediatric Otorhinolaryngology·Michal GreenfeldYakov Sivan
Mar 5, 2010·Respirology : Official Journal of the Asian Pacific Society of Respirology·Stanley D W MillerWalter T McNicholas
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Oct 31, 2009·Journal of Applied Physiology·Raanan Arens, Hiren Muzumdar
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Jul 20, 2005·The Journal of Pediatrics·Arlen Denny, Christian Amm
Jul 21, 2016·Archives of Disease in Childhood. Fetal and Neonatal Edition·Wolfgang BuchenauChristian F Poets
Nov 7, 2015·The European Respiratory Journal·Athanasios G KaditisStijn Verhulst
Nov 17, 2005·Journal of Applied Physiology·Clodagh M Ryan, T Douglas Bradley
May 1, 1996·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·P D WittG P Watchmaker
Jul 25, 2019·Plastic and Reconstructive Surgery. Global Open·Dennis O Frank-ItoJeffrey R Marcus
May 1, 1992·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·K Glander, G J Cisneros

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