Sleep, inflammation, and perception of sad facial emotion: A laboratory-based study in older adults.

Brain, Behavior, and Immunity
Dominique PiberMichael R Irwin

Abstract

Facial emotion perception (FEP) is pivotal for discriminating salient emotional information. Accumulating data indicate that FEP responses, particularly to sad emotional stimuli, are impaired in depression. This study tests whether sleep disturbance and inflammation, two risk factors for depression, contribute to impaired FEP to sad emotional stimuli. In older adults (n = 40, 71.7 ± 6.8y, 56.4% female), disturbance of sleep maintenance (i.e., wake time after sleep onset [WASO]) was evaluated by polysomnography. In the morning, plasma concentrations of two markers of systemic inflammation were evaluated (i.e., interleukin [IL]-6, tumor necrosis factor [TNF]-α), followed by two FEP tasks, which assessed delays in emotion recognition (ER) and ratings of perceived emotion intensity (EI) in response to sad facial emotional stimuli, with exploration of FEP responses to happiness and anger. Linear regression models tested whether WASO, IL-6, and TNF-α would be associated with impaired FEP to sad emotional stimuli. In addition, moderation tests examined whether inflammation would moderate the link between sleep disturbance and impaired FEP to sad emotional stimuli. Longer WASO predicted longer ER delays (p < 0.05) and lower EI ratings ...Continue Reading

References

Sep 1, 1980·Journal of Personality and Social Psychology·D RussellC E Cutrona
Dec 1, 1996·Journal of Personality Assessment·A T BeckW Ranieri
Aug 31, 2002·Psycho-oncology·Frank BakerWilliam N Dudley
Aug 30, 2003·Biological Psychiatry·Mary L PhillipsRichard Lane
Dec 1, 2005·The International Journal of Neuropsychopharmacology·Helen R VennAllan H Young
Oct 5, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Frederik M van der VeenJeroen A J Schmitt
Feb 16, 2008·Neuroscience and Biobehavioral Reviews·Ted RuffmanLouise H Phillips
Mar 18, 2008·Psychiatry Research·Jackie K GollanEmil F Coccaro
Sep 4, 2008·The American Journal of Psychiatry·Hyong Jin ChoMichael R Irwin
Dec 9, 2008·Cognition·Seth D PollakJeffrey F Cohn
Aug 12, 2009·Neuroscience and Biobehavioral Reviews·Nicole DellaGioia, Jonas Hannestad
Dec 18, 2009·Biological Psychiatry·Yekta DowlatiKrista L Lanctôt
Mar 27, 2010·Sleep·Els van der HelmMatthew P Walker
Jul 20, 2010·The Australian and New Zealand Journal of Psychiatry·Cecilia BourkeRichard Porter
May 24, 2011·Psychiatry Research·Christian G KohlerPaul J Moberg
Sep 13, 2011·International Journal of Environmental Research and Public Health·Eleni AndreouChristina Darviri
Jan 17, 2012·Neuropsychologia·M E Kret, B De Gelder
May 24, 2012·The Behavioral and Brain Sciences·Kristen A LindquistLisa Feldman Barrett
Oct 16, 2012·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Richard B BerryUNKNOWN American Academy of Sleep Medicine
Nov 13, 2012·Annual Review of Physiology·Judith Campisi
Apr 3, 2013·Social Cognitive and Affective Neuroscience·Jennifer S KullmannElke R Gizewski
Feb 7, 2014·Annual Review of Clinical Psychology·Andrea N Goldstein, Matthew P Walker
Jun 6, 2014·Sleep·Simon D KyleColin A Espie
Jul 16, 2014·Frontiers in Psychology·Stefano Anzellotti, Alfonso Caramazza
Jul 26, 2014·Annual Review of Psychology·Michael R Irwin
Nov 15, 2014·Psychological Medicine·M N DaliliM R Munafò
Mar 15, 2015·Brain, Behavior, and Immunity·Mona MoieniNaomi I Eisenberger
Oct 20, 2015·Sleep Medicine Reviews·Shawn D YoungstedtGirardin Jean-Louis
Dec 30, 2015·Nature Reviews. Immunology·Andrew H Miller, Charles L Raison

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