Sleep Quality Effects Recovery After Total Knee Arthroplasty (TKA) - A Randomized, Double-Blind, Controlled Study

The Journal of Arthroplasty
Long GongDong Fan

Abstract

This study examined the effects of sleep quality on early recovery after total knee arthroplasty. A total of 148 patients were randomized 1:1 to receive either zolpidem or placebo for 2weeks. VAS pain scores (rest, ambulation and night), range of motion (ROM), total amount of opioid analgesics and antiemetics taken, postoperative nausea and vomiting (PONV), sleep efficacy and satisfaction were recorded. It was found that patients taking zolpidem achieved greater improvement in quality of life and reported better satisfaction. Patients in the intervention group had lower pain score and took less antiemetics. Moreover, a significant correlation between sleep quality and ROM was detected. These results demonstrated that improved sleep quality is beneficial to patients' post-TKA recovery.

Associated Clinical Trials

References

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Citations

Dec 16, 2016·European Journal of Pain : EJP·S Orbach-ZingerR Landau
Aug 19, 2016·The Journal of Bone and Joint Surgery. American Volume·Thomas W HamiltonHemant G Pandit
Jan 19, 2017·The Journal of Bone and Joint Surgery. American Volume·Gwo-Chin Lee
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Feb 15, 2019·Pain Practice : the Official Journal of World Institute of Pain·Martin F Bjurström, Michael R Irwin
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Nov 10, 2017·Current Opinion in Anaesthesiology·Xian Su, Dong-Xin Wang
May 5, 2018·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Toby N WeingartenMichael L Kent
Sep 20, 2020·The Journal of Arthroplasty·Jan P Van MeirhaegheJustin P Roe
Nov 14, 2020·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Kyle N KunzeShane J Nho
Mar 29, 2021·The Spine Journal : Official Journal of the North American Spine Society·Majd MarracheRichard L Skolasky
Jul 30, 2020·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Nicholas A GiordanoKrista Beth Highland
Aug 29, 2021·International Orthopaedics·Ravi Kumar MukartihalSharan S Patil
Sep 4, 2021·The Journal of Bone and Joint Surgery. American Volume·Gabrielle BeetzDominique M Rouleau
Sep 4, 2021·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Andres F BarandiaranJonathan T Bravman
Nov 2, 2021·The Journal of the American Academy of Orthopaedic Surgeons·Samuel J ClarksonJames J Purtill

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