PMID: 7932283May 1, 1994Paper

Sleep-related growth hormone secretion is persistently suppressed in women with recurrent depression: a preliminary longitudinal analysis

Journal of Psychiatric Research
D B JarrettB Franz

Abstract

Growth hormone secretion was monitored during sleep in a group of 43 women with recurrent major depression who were participating in a 3-year maintenance therapy program. Patients were studied before acute treatment, after complete remission, and at 3-month intervals during maintenance treatment and the data generated were compared to those obtained in a control group of 14 age-matched healthy women studied once under identical conditions. When compared to the control group, the depressed patients secreted significantly less growth hormone before treatment. This reduction in growth hormone secretion, which was confined to the first half of the sleep period, persisted across the length of the maintenance study regardless of whether the subjects completed three years of therapy or experienced a recurrence.

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Citations

May 1, 1994·Journal of Psychiatric Research·J C Gillin
Jun 5, 1998·Progress in Neuro-psychopharmacology & Biological Psychiatry·P N SakkasC N Stefanis
Dec 4, 2003·Journal of Child and Adolescent Psychopharmacology·Kristine ColemanJudy L Cameron
May 16, 2013·Reproductive Biology and Endocrinology : RB&E·Juan J TarínAntonio Cano
Dec 1, 1995·Biological Psychiatry·B FranzV J Grochocinski
Jan 7, 2015·Acta Physiologica·A S UrrilaM Marttunen
Jul 23, 2003·Journal of Psychopharmacology·B RijnbeekJ M A van Gerven
Nov 21, 2019·Molecular Psychiatry·Mitzy KennisClaudi Bockting

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