PMID: 42497Nov 1, 1979

Sleep-wake patterns and integrated values of luteinizing hormone, follicle stimulating hormone, prolactin, growth hormone and thyroid stimulating hormone in normal and cryptorchid pubertal patients

Clinical Endocrinology
M GiustiG Giordano


The sleep-wake behaviour of LH, FSH, PRI, GH and TSH was studied in seven cryptorchid patients (four unilateral and three bilateral cryptorchids) average age 12 years and in nine normal pubertal boys of 13 years (mean age). Blood samples were collected by a continuous withdrawal pump, every hour, for 24 h. The hormonal concentration for every fraction of time was measured and related to the sleep (Sc-), wake (Wc-) and total 24 h period (Dc-). The integrated concentrations of the corresponding periods (IS, IW, ID) were calculated as well as their ratios (IS/IW; IS/ID%). For GH and TSH, the data obtained demonstrated no differences between cryptorchid and pubertal subjects. The PRL secretion in cryptorchid patients was moderately increased during the hours of nocturnal sleep. A normal pubertal sleep-wake rhythm was found for gonadotrophins in both groups of subjects. More marked levels of LH secretion were observed in cryptorchid boys compared to normal pubertals. The presence of a sleep-wake rhythm was also found in the cryptorchid patients and normal pubertal subjects in the P 1 stage. These data suggest that the CNS "programme" which controls the onset of puberty may be normal in cryptorchid patients.


Aug 31, 2011·Thyroid : Official Journal of the American Thyroid Association·Francoise Brucker-DavisPatrick Fenichel
Oct 1, 1984·Clinical Endocrinology·M GiustiG Giordano
Feb 12, 2008·Otolaryngologia polska. The Polish otolaryngology·Piotr RapiejkoDariusz Jurkiewicz
Jan 1, 1985·European Archives of Psychiatry and Neurological Sciences·C M BankiZ Kovacs


Sep 1, 1976·Acta paediatrica Scandinavica·P E Waaler
Jul 1, 1977·Acta Endocrinologica·J C JobJ L Chaussain
Jul 1, 1977·The Journal of Pediatrics·M Vanderschueren-Lodeweyckx
Jan 1, 1977·Hormone Research·J C JobP E Garnier
Jun 1, 1975·The Journal of Clinical Endocrinology and Metabolism·Z LaronE Halabe
Sep 1, 1977·Acta Endocrinologica·C LuckeA von zur Mühlen
May 1, 1977·The Journal of Clinical Endocrinology and Metabolism·H L JuddS S Yen
Jul 1, 1976·The Journal of Clinical Endocrinology and Metabolism·P A LeeR M Blizzard
Feb 1, 1975·The Journal of Clinical Endocrinology and Metabolism·L P PlotnickR M Blizzard
Jul 1, 1973·The Journal of Clinical Endocrinology and Metabolism·P C SizonenkoL Paunier
Apr 1, 1974·American Journal of Diseases of Children·P A LeeR M Blizzard
Sep 21, 1972·The New England Journal of Medicine·R BoyarL Hellman
Oct 1, 1973·The Journal of Clinical Endocrinology and Metabolism·F P AlfordH G Burger
Oct 1, 1970·The Journal of Clinical Investigation·J T NicoloffM D Appleman
Jul 1, 1972·Clinical Science·Y C PatelH G Burger
Mar 1, 1971·The Journal of Clinical Endocrinology and Metabolism·A KowarskiR M Blizzard

Related Concepts

Growth Hormone Activity
Pituitary Hormones, Anterior
Sleep, Slow-Wave
Follicle Stimulating Hormone Measurement
Process of Secretion
PRL gene
Growth Hormone Measurement

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