PMID: 42497Nov 1, 1979

Sleep-wake patterns and integrated values of luteinizing hormone, follicle stimulating hormone, prolactin, growth hormone and thyroid stimulating hormone in normal and cryptorchid pubertal patients

Clinical Endocrinology
M GiustiG Giordano

Abstract

The sleep-wake behaviour of LH, FSH, PRI, GH and TSH was studied in seven cryptorchid patients (four unilateral and three bilateral cryptorchids) average age 12 years and in nine normal pubertal boys of 13 years (mean age). Blood samples were collected by a continuous withdrawal pump, every hour, for 24 h. The hormonal concentration for every fraction of time was measured and related to the sleep (Sc-), wake (Wc-) and total 24 h period (Dc-). The integrated concentrations of the corresponding periods (IS, IW, ID) were calculated as well as their ratios (IS/IW; IS/ID%). For GH and TSH, the data obtained demonstrated no differences between cryptorchid and pubertal subjects. The PRL secretion in cryptorchid patients was moderately increased during the hours of nocturnal sleep. A normal pubertal sleep-wake rhythm was found for gonadotrophins in both groups of subjects. More marked levels of LH secretion were observed in cryptorchid boys compared to normal pubertals. The presence of a sleep-wake rhythm was also found in the cryptorchid patients and normal pubertal subjects in the P 1 stage. These data suggest that the CNS "programme" which controls the onset of puberty may be normal in cryptorchid patients.

References

Aug 31, 2011·Thyroid : Official Journal of the American Thyroid Association·Francoise Brucker-DavisPatrick Fenichel
Oct 1, 1984·Clinical Endocrinology·M GiustiG Giordano
Feb 12, 2008·Otolaryngologia polska. The Polish otolaryngology·Piotr RapiejkoDariusz Jurkiewicz
Jan 1, 1985·European Archives of Psychiatry and Neurological Sciences·C M BankiZ Kovacs

Citations

Sep 1, 1976·Acta paediatrica Scandinavica·P E Waaler
Jul 1, 1977·Acta Endocrinologica·J C JobJ L Chaussain
Jul 1, 1977·The Journal of Pediatrics·M Vanderschueren-Lodeweyckx
Jan 1, 1977·Hormone Research·J C JobP E Garnier
Jun 1, 1975·The Journal of Clinical Endocrinology and Metabolism·Z LaronE Halabe
Sep 1, 1977·Acta Endocrinologica·C LuckeA von zur Mühlen
May 1, 1977·The Journal of Clinical Endocrinology and Metabolism·H L JuddS S Yen
Jul 1, 1976·The Journal of Clinical Endocrinology and Metabolism·P A LeeR M Blizzard
Feb 1, 1975·The Journal of Clinical Endocrinology and Metabolism·L P PlotnickR M Blizzard
Jul 1, 1973·The Journal of Clinical Endocrinology and Metabolism·P C SizonenkoL Paunier
Apr 1, 1974·American Journal of Diseases of Children·P A LeeR M Blizzard
Sep 21, 1972·The New England Journal of Medicine·R BoyarL Hellman
Oct 1, 1973·The Journal of Clinical Endocrinology and Metabolism·F P AlfordH G Burger
Oct 1, 1970·The Journal of Clinical Investigation·J T NicoloffM D Appleman
Jul 1, 1972·Clinical Science·Y C PatelH G Burger
Mar 1, 1971·The Journal of Clinical Endocrinology and Metabolism·A KowarskiR M Blizzard

Related Concepts

Growth Hormone Activity
Cryptorchidism
Pituitary Hormones, Anterior
Sleep, Slow-Wave
Luteozyman
Follicle Stimulating Hormone Measurement
Process of Secretion
Thyrotropin
PRL gene
Growth Hormone Measurement

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.