Sleeve Gastrectomy Postoperative Hemorrhage is Linked to Type-2 Diabetes and Not to Surgical Technique

Obesity Surgery
Hadar SpivakOrit Blumenfeld

Abstract

The degree, prevalence, and risk factors linked to sleeve gastrectomy (SG) postoperative hemorrhage (POH) have not been fully defined. An analysis was conducted on a prospectively collected database of 394 consecutive primary SGs performed in a single practice from January 2014 to December 2015. (1) acute POH, defined by red blood cell (RBC) transfusion and/or re-exploration; (2) subclinical POH, defined by postoperative hemoglobin drop (HgbD) >one standard deviation above mean. Variables tested included three surgical techniques: normal stapling (n = 137), "tight" stapling, (n = 142) and oversewing, (n = 115); age; gender; body mass index (BMI); co-morbidities; and elevated postoperative systolic blood pressure. Acute POH occurred in 11/394 patients (2.8%) and subclinical POH (HgbD > 2.2 g/dL) was detected in 27/312 (7.7%) of patients with available HgbD data. Acute POH patients had a mean HgbD of 5.43 ± 1.40 g/dl (p < 0.001) reflecting approximately 38.6% ± 10.0% of total blood volume. No difference in prevalence of POH was observed for the different surgical techniques. Compared with non-bleeders (n = 312), acute and subclinical POH patients (n = 38) had 52.6 vs. 27.2% prevalence type-2 diabetes (T2D) and 60.5 vs. 40.1% prev...Continue Reading

References

Mar 22, 2001·Journal of Diabetes and Its Complications·M E Carr
Jul 27, 2001·Diabetes Care·A I VinikG L Pittenger
May 4, 2007·The Journal of Clinical Investigation·Harold Brem, Marjana Tomic-Canic
Jul 3, 2009·The Journal of Bone and Joint Surgery. American Volume·Milford H MarchantMichael P Bolognesi
Jul 30, 2009·Annals of Surgery·Pierre A ClavienMasatoshi Makuuchi
Jul 20, 2010·Journal of Thrombosis and Thrombolysis·Armando TripodiPier Mannuccio Mannucci
Aug 2, 2011·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Philippe TopartPatrick Ritz
Dec 20, 2011·Surgical Endoscopy·Alexander R AuroraAlan A Saber
Jan 11, 2013·Physiological Reviews·Henri H VersteegPieter H Reitsma
Apr 22, 2014·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Michel Gagner, Jane N Buchwald
Jun 26, 2015·British Journal of Anaesthesia·P TzimasG Papadopoulos
Oct 20, 2015·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Jaime PonceJohn M Morton
Jun 10, 2016·Obesity Surgery·Mousa KhoursheedAbe Fingerhut
Jan 13, 2017·Obesity Surgery·Frank BenedixUNKNOWN Obesity Surgery Working Group Competence Network Obesity

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