Sliding characteristic and material compressibility of human lung: parametric study and verification.

Medical Physics
Adil Al-MayahK K Brock

Abstract

To find and verify the optimum sliding characteristics and material compressibility that provide the minimum error in deformable image registration of the lungs. A deformable image registration study has been conducted on a total of 16 lung cancer patients. Patient specific three dimensional finite element models have been developed to model left and right lungs, chest (body), and tumor based on 4D CT images. Contact surfaces have been applied to lung-chest cavity interfaces. Experimental test data are used to model nonlinear material properties of lungs. A parametric study is carried out on seven patients, 20 conditions for each, to investigate the sliding behavior and the tissue compressibility of lungs. Three values of coefficient of friction of 0, 0.1, and 0.2 are investigated to model lubrication and sliding restriction on the lung-chest cavity interface. The effect of material compressibility of lungs is studied using Poisson's ratios of 0.35, 0.4, 0.45, and 0.499. The model accuracy is examined by calculating the difference between the image-based displacement of bronchial bifurcation points identified in the lung images and the calculated corresponding model-based displacement. Furthermore, additional bifurcation points...Continue Reading

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Citations

Jul 8, 2011·Physics in Medicine and Biology·Adil Al-MayahKristy Brock
May 15, 2012·Physics in Medicine and Biology·Hualiang ZhongIndrin J Chetty
Oct 21, 2011·Critical Reviews in Biomedical Engineering·Merryn TawhaiK Burrowes
Jan 10, 2012·Medical Physics·Xiangfei ChaiArjan Bel
Aug 18, 2012·Computer Aided Surgery : Official Journal of the International Society for Computer Aided Surgery·Ali Sadeghi-NainiAbbas Samani
Oct 25, 2014·IEEE Transactions on Medical Imaging·Bernhard FuerstAli Kamen
May 28, 2013·Journal of the Mechanical Behavior of Biomedical Materials·Michael TakazaCiaran K Simms
Nov 11, 2016·IEEE Transactions on Medical Imaging·You ZhangJing Wang
Jun 11, 2020·Medical Physics·Brad StiehlAnand P Santhanam
Apr 2, 2015·Physics in Medicine and Biology·Navid SamavatiKristy Brock
Nov 5, 2015·Physics in Medicine and Biology·Joubin Nasehi TehraniJing Wang
Aug 9, 2020·Physics in Medicine and Biology·Cornel ZachiuMario G Ries
Feb 2, 2021·Computers in Biology and Medicine·Parya JafariAbbas Samani
Feb 23, 2021·Medical Physics·Guillaume CazoulatKristy K Brock

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