PMID: 8942894Nov 1, 1996Paper

Slit-lamp needle revision of failed filtering blebs using mitomycin C

Ophthalmology
P G MardelliK M Hassanein

Abstract

The purpose of the study is to determine the efficacy and safety of Mitomycin C (MMC) augmented slit-lamp needle revision of failed filtration surgery. The authors retrospectively reviewed the charts of 62 patients (62 eyes) (age, 72 +/- 15 years) with failed filtration surgery who underwent needle revision using MMC. A mixture of 0.01 ml of MMC (0.4 mg/ml) and 0.02 ml of bupivacaine with epinephrine was injected subconjunctivally. Twenty to 30 minutes later, a 30-gauge needle was used to perforate the area of subconjunctival fibrosis and re-establish flow. Overall, 118 needing procedures (mean, 1.9 +/- 1.4 revisions per eye; range, 1-7) were performed on 62 eyes (mean follow-up, 9.9 +/- 3.7 months; range, 4.5-20.1 months). Thirty-six patients (58.1%) were needled once and 26 patients (41.9%) underwent more than 1 needling procedure. Intraocular pressure decreased from 24.1 +/- 6.4 mmHg (range, 18-44) before surgery to 11.5 +/- 4.8 mmHg (range, 1-26) at last follow-up (P = 5.51 x 10(-21)). Antiglaucoma medications decreased from 1.6 +/- 1.0 to 0.3 +/- 0.6 (P = 3.8 x 10(-14)). Successful single-needling procedure was highly correlated with race (white) and past conventional glaucoma filtration surgery of more than 4 years. Compl...Continue Reading

References

Sep 1, 1977·Archives of Ophthalmology·J S CohenD Hoskins
Mar 1, 1991·Ophthalmology·S S Palmer
Jan 1, 1990·Ophthalmology·B J ShingletonB T Hutchinson
Sep 15, 1990·American Journal of Ophthalmology·R H Ewing, R L Stamper
Nov 1, 1987·Survey of Ophthalmology·G L Skuta, R K Parrish
Jul 1, 1985·Ophthalmology·J E Pederson, S G Smith
Sep 1, 1982·Ophthalmology·W M Grant, J F Burke
Nov 1, 1995·American Journal of Ophthalmology·A L ColemanW C Panek
Feb 1, 1995·Archives of Ophthalmology·C KeeP L Kaufman
Apr 1, 1994·Archives of Ophthalmology·M L McDermottD H Shin
Jul 15, 1993·American Journal of Ophthalmology·A MermoudA D Murray

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Citations

Mar 21, 2007·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M MüllerH Laqua
Dec 4, 2003·American Journal of Ophthalmology·Padmanabha Pillai SyamNitin Anand
Oct 8, 1998·Survey of Ophthalmology·A Azuara-Blanco, L J Katz
Feb 20, 1999·Survey of Ophthalmology·W L Haynes, W L Alward
Apr 3, 2002·Ophthalmology·Anjali S HawkinsSteven V L Brown
Apr 12, 2003·Ophthalmology·Andrew G IwachPatricia C Wong
Jul 15, 1998·Ophthalmology·D S LamD S Fan
Jun 27, 2012·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Tulay SimsekUfuk Elgin
Nov 12, 2003·The British Journal of Ophthalmology·C T UngK G Claridge
Dec 25, 2010·Middle East African Journal of Ophthalmology·Thanaa Helmy Mohamed Elsayed, Tamer Mohamed El-Raggal
May 25, 2012·Middle East African Journal of Ophthalmology·Heidar AminiRamin Daneshvar
Aug 15, 2013·International Ophthalmology·Yadollah EslamiSasan Moghimi
Jan 15, 2005·Journal of Glaucoma·Rajesh K ShettyMarlene R Moster
Aug 19, 2007·Journal of Glaucoma·Nitin Anand, Seema Arora
Oct 16, 2008·Journal of Glaucoma·Robert M Feldman, Rania R Tabet
Feb 27, 2015·Journal of Glaucoma·Linda ZhengDavid Wechsler
Jun 24, 2008·Journal of Cataract and Refractive Surgery·Pierre G Mardelli
Dec 4, 2003·Acta Ophthalmologica Scandinavica·Marit FagerliTor Elsås
Aug 8, 2015·Acta Ophthalmologica·Sanaa A Yassin
Sep 1, 2015·Journal of Glaucoma·Evan J AllanMahmoud A Khaimi
Oct 12, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Antigoni KoukkoulliNitin Anand
Nov 10, 2015·Journal of Glaucoma·Divya MathewsAdesuwa Garrick
Dec 18, 2007·Ophthalmology·Alan P Rotchford, Anthony J W King
Mar 8, 2016·Journal of Glaucoma·Joseph F PanarelliPaul A Sidoti
Dec 14, 2011·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Fariha ShafiVelota Sung
Dec 14, 2016·Indian Journal of Ophthalmology·Maria Tulidowicz-BielakTomasz Żarnowski
May 10, 2017·Journal of Glaucoma·Davinder S Grover, Ronald L Fellman

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