PMID: 6410354May 1, 1983Paper

Slow amphibian muscle fibres become less sensitive to Ca2+ with increasing sarcomere length

Pflügers Archiv : European journal of physiology
D G Stephenson, D A Williams

Abstract

Here we report that mechanically skinned muscle preparations from slow amphibian muscle fibres become less sensitive to Ca2+ when the sarcomere length is increased beyond the value corresponding to optimum filament overlap. This effect is opposite to that observed in all other studies on vertebrate myofibrillar preparations from twitch (Endo, 1972a; 1972b; Moisescu & Thieleczek, 1979; Stephenson & Williams, 1982) and cardiac muscles (Fabiato & Fabiato, 1978). This finding shows that stretch-induced increased in Ca2+ sensitivity is not a general property of the contractile apparatus and suggests that differences in the ultrastructure between these muscle fibre types could be responsible for the opposite length effects. Furthermore, these results allow a more detailed understanding of the processes behind the stretch effects observed in intact slow and twitch amphibian muscle fibres (Lännergren, 1975).

References

Apr 11, 1979·Biochimica Et Biophysica Acta·D G Moisescu, R Thieleczek
Feb 1, 1976·The Journal of Physiology·E Stefani, O D Uchitel
Jan 1, 1975·Tissue & Cell·W F Gilly
May 2, 1970·Nature·G F ElliottM Spencer
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Sep 1, 1981·The Journal of Physiology·R MilediG Schalow

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Citations

Sep 1, 1985·Pflügers Archiv : European journal of physiology·G J StienenB W Treijtel
Nov 16, 1993·European Journal of Pharmacology·P SchiereckA Bavinck
Jan 1, 1987·Pflügers Archiv : European journal of physiology·G J StienenG Elzinga
Apr 1, 1988·The American Journal of Physiology·E L de BeerP Schiereck
Jul 1, 1987·The American Journal of Physiology·P A Hofmann, F Fuchs
Feb 1, 1993·Journal of Muscle Research and Cell Motility·D A MartynA M Gordon
Sep 24, 2005·American Journal of Physiology. Cell Physiology·Brett O'ConnellGabriela M M Stephenson
Dec 1, 1990·The American Journal of Physiology·R L Ruff, P Spiegel

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