PMID: 8592211Nov 1, 1995Paper

Slow and saccadic eye movements evoked by microstimulation in the supplementary eye field of the cebus monkey

Journal of Neurophysiology
J-R Tian, J C Lynch

Abstract

1. Intracortical microstimulation was used to map the supplementary eye field (SEF) in eight hemispheres of five Cebus apella monkeys. Monkeys were immobilized during experiments with Telazol (tiletamine HCl and zolazepam HCl), a dissociative anesthetic agent that was demonstrated to have no significant effect on microstimulation-induced eye movement parameters compared with similar experiments in alert, behaviorally trained monkeys. The functional subregions were defined with the use of low-threshold current (< or = 50 microA). Electrically elicited eye movements were videotaped and quantified. Both slow and saccadic eye movements were reliably evoked at low threshold by microstimulation in each of eight hemispheres studied. The two types of eye movements were clearly distinguished by their significantly different duration and velocity (P < 0.0001) and their different responses to long stimulus trains. The results strongly support the proposal that the SEF produces not only saccadic eye movements as previously reported but also slow (pursuit) eye movements.

Citations

Jan 11, 2002·Journal of Neurophysiology·Léon TremblayCarl R Olson
Sep 16, 2005·Journal of Neurophysiology·Junghyun ParkJohn Schlag
Jan 27, 2007·Cerebral Cortex·Anthony S Drew, Paul van Donkelaar
Nov 6, 2014·Experimental Brain Research·Supriya Ray, Stephen J Heinen
Feb 6, 2004·Journal of Neurophysiology·Richard J Krauzlis
Mar 1, 2017·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Marcus Missal, Stephen J Heinen
Nov 12, 2017·The Journal of Comparative Neurology·Iwona StepniewskaJon H Kaas
Aug 17, 2004·Experimental Brain Research·G R BarnesL R Arnold
Aug 28, 2004·Journal of Neurophysiology·G R Barnes, G D Paige
Jul 13, 1999·Journal of Neurophysiology·L Petit, J V Haxby
Jul 28, 2005·The European Journal of Neuroscience·Michele A BassoPing Liu
Nov 14, 2008·Brain and Cognition·James A Sharpe

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