Slow early growers have more muscle in relation to adult activity: evidence from Cebu, Philippines

European Journal of Clinical Nutrition
M WorkmanChristopher Kuzawa

Abstract

Adult skeletal muscle mass (SMM) protects against type 2 diabetes, but little is known about its developmental antecedents. We examined whether pace of early weight gain predicted adult SMM in a birth cohort from Cebu City, Philippines. In addition, we examined whether increases in SMM associated with adult muscle-building exercise varied according to the early growth. Data came from 1472 participants of the Cebu Longitudinal Health and Nutrition Survey. Weight was measured at birth and at 6-month intervals through the age of 24 months. Adult SMM was estimated from anthropometric measurements when participants were 20-22-years old. Interviews provided the information on adult exercise/lifestyle habits. SMM (mean ± s.d.) was 20.8 ± 3.9 kg (men) and 13.6 ± 3.4 kg (women). Faster early weight gain predicted a higher adult SMM. After adjustment for height and lifestyle factors, strongest associations with SMM were found for 6-12 months growth in men (β=0.17, P=0.001) and for birth weight in women (β=0.14, P=0.001). Individuals who had grown slowly displayed greater SMM in association with adult weightlifting, basketball playing and physically demanding forms of employment (men) or household chores (women). These results suggest hei...Continue Reading

References

Nov 1, 1979·The Journal of Pediatrics·J L BallardM Driver
Jul 1, 1988·Journal of Biological Standardization·A F Bristow, R E Das
Oct 1, 1982·The American Journal of Clinical Nutrition·S B HeymsfieldD W Nixon
Jul 1, 1997·Journal of Applied Physiology·D GallagherS B Heymsfield
Jan 23, 1999·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·G E McCallW J Kraemer
Sep 14, 1999·Journal of Applied Physiology·W J KraemerW J Evans
Jul 6, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·H S KahnR Valdez
Aug 10, 2000·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·B C NindlW C Hymer
Nov 15, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·F M IveyB F Hurley
Oct 24, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·R J LoosR Vlietinck
Feb 12, 2002·American Journal of Epidemiology·A Colin BellBarry M Popkin
Mar 28, 2002·International Journal of Sport Nutrition and Exercise Metabolism·B C NindlS J Fleck
Mar 28, 2002·The American Journal of Clinical Nutrition·Ruth J F LoosRobert Vlietinck
Sep 24, 2002·American Journal of Epidemiology·Diana KuhCyrus Cooper
Nov 1, 2002·American Journal of Physical Medicine & Rehabilitation·Michael R Deschenes, William J Kraemer
Jun 7, 2003·The American Journal of Clinical Nutrition·Haojie LiReynaldo Martorell
Sep 30, 2003·Journal of Applied Physiology·Mark S TremblayWalter Van Helder
Jun 23, 2004·Preventive Medicine·Johan G ErikssonDavid J P Barker
Jun 24, 2004·The American Journal of Clinical Nutrition·Avan Aihie SayerDavid I Phillips
Apr 9, 2005·Journal of Applied Physiology·Priscilla M ClarksonJoseph M Devaney
Aug 17, 2005·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J C K WellsC G Victora
Jun 16, 2006·Medicine and Science in Sports and Exercise·Linda S PescatelloEric P Hoffman
Mar 16, 2007·International Journal of Obesity : Journal of the International Association for the Study of Obesity·H YlihärsiläJ G Eriksson
Jul 21, 2007·Proceedings of the National Academy of Sciences of the United States of America·Kitt Falk PetersenGerald I Shulman
Aug 19, 2007·Journal of Internal Medicine·H M InskipUNKNOWN Southampton Women's Survey Study Group
Jan 22, 2008·Lancet·Cesar G VictoraUNKNOWN Maternal and Child Undernutrition Study Group
Apr 28, 2009·Metabolism: Clinical and Experimental·Evan AtlantisUNKNOWN Members of the Florey Adelaide Male Ageing Study
May 28, 2009·JAMA : the Journal of the American Medical Association·Juliana C N ChanFrank B Hu
Nov 13, 2009·Diabetes Care·Ralph A DeFronzo, Devjit Tripathy
Mar 24, 2010·American Journal of Physical Anthropology·Lee T GettlerChristopher W Kuzawa
May 29, 2010·International Journal of Epidemiology·Linda S AdairMichelle J Hindin
Sep 15, 2010·Proceedings of the National Academy of Sciences of the United States of America·Christopher W KuzawaNanette Lee
Jul 23, 2011·The Journal of Clinical Endocrinology and Metabolism·Preethi Srikanthan, Arun S Karlamangla
Nov 29, 2011·American Journal of Human Biology : the Official Journal of the Human Biology Council·Christopher W KuzawaUNKNOWN COHORTS Group
Aug 8, 2012·Archives of Internal Medicine·Anders GrøntvedFrank B Hu
Aug 14, 2013·European Journal of Endocrinology·Leontine E H BakkerIngrid M Jazet

❮ Previous
Next ❯

Citations

Dec 19, 2015·American Journal of Human Biology : the Official Journal of the Human Biology Council·Megan WorkmanJoe Alcock

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.