Slow skeletal muscles of the mouse have greater initial efficiency than fast muscles but the same net efficiency

The Journal of Physiology
C J Barclay, C L Weber

Abstract

The aim of this study was to determine whether the net efficiency of mammalian muscles depends on muscle fibre type. Experiments were performed in vitro (35 degrees C) using bundles of muscle fibres from the slow-twitch soleus and fast-twitch extensor digitorum longus (EDL) muscles of the mouse. The contraction protocol consisted of 10 brief contractions, with a cyclic length change in each contraction cycle. Work output and heat production were measured and enthalpy output (work + heat) was used as the index of energy expenditure. Initial efficiency was defined as the ratio of work output to enthalpy output during the first 1 s of activity. Net efficiency was defined as the ratio of the total work produced in all the contractions to the total, suprabasal enthalpy produced in response to the contraction series, i.e. net efficiency incorporates both initial and recovery metabolism. Initial efficiency was greater in soleus (30 +/- 1%; n=6) than EDL (23 +/- 1%; n=6) but there was no difference in net efficiency between the two muscles (12.6 +/- 0.7% for soleus and 11.7 +/- 0.5% for EDL). Therefore, more recovery heat was produced per unit of initial energy expenditure in soleus than EDL. The calculated efficiency of oxidative phos...Continue Reading

References

May 1, 1978·The Journal of General Physiology·M Mahler
Nov 1, 1977·The American Journal of Physiology·L A MulieriN R Alpert
Jul 1, 1992·Medicine and Science in Sports and Exercise·E F CoyleJ D Beltz
Apr 1, 1990·Pflügers Archiv : European journal of physiology·W J Leijendekker, G Elzinga
Jul 1, 1987·The American Journal of Physiology·N C Heglund, G A Cavagna
Dec 1, 1985·Journal of Muscle Research and Cell Motility·S J Smith, R C Woledge
May 25, 1972·Biochimica Et Biophysica Acta·J Rosing, E C Slater
Mar 29, 1974·Radiation and Environmental Biophysics·J BückingP Piontek
May 1, 1973·The American Journal of Physiology·I R Wendt, C L Gibbs
Oct 1, 1972·The American Journal of Physiology·C L Gibbs, W R Gibson
Aug 1, 1968·The Journal of Physiology·R C Woledge
May 15, 1965·Nature·R Close
Jan 1, 1983·Advances in Experimental Medicine and Biology·M J KushmerickT R Brown
Dec 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·C W HeizmannA M Rowlerson
Jan 1, 1982·The Journal of General Physiology·M T Crow, M J Kushmerick
Nov 1, 1994·Medicine and Science in Sports and Exercise·B J Whipp
Jan 1, 1993·Advances in Experimental Medicine and Biology·M J KushmerickR W Wiseman
Dec 1, 1993·The Journal of Physiology·C J BarclayC L Gibbs
Nov 1, 1995·The Journal of Physiology·C J BarclayC L Gibbs
Dec 15, 1996·The Journal of Physiology·C J Barclay
Apr 4, 1998·Pflügers Archiv : European journal of physiology·A ArdévolM Alemany
Jul 15, 1999·Physiology & Behavior·K A Clarke, J Still
May 15, 2001·Biochemical and Biophysical Research Communications·G B MooreJ C Clapham
Jul 9, 2003·The Journal of Experimental Biology·C J BarclayL J Mellors
Jan 14, 1964·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·A V HILL
Jun 3, 2004·The Journal of General Physiology·Andrew G Szent-Györgyi

❮ Previous
Next ❯

Citations

Oct 27, 2004·European Journal of Applied Physiology·K KoppoJ Bouckaert
Sep 10, 2013·Pflügers Archiv : European journal of physiology·D B Lewis, C J Barclay
Feb 9, 2012·The Journal of Physiology·S Park-HolohanG Piazzesi
Aug 4, 2010·The Journal of Physiology·C J BarclayN A Curtin
Nov 15, 2006·Journal of Biomechanics·G A Lichtwark, A M Wilson
Dec 3, 2005·Journal of Muscle Research and Cell Motility·C J Barclay
Sep 12, 2017·Clinical and Experimental Pharmacology & Physiology·Christopher J Barclay
Apr 27, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Masako Yamaoka EndoYoshiyuki Fukuba
Apr 17, 2013·Journal of Applied Physiology
Dec 24, 2015·Medicine and Science in Sports and Exercise·Gwenael LayecDavid Bendahan
Sep 25, 2019·Research : a Science Partner Journal·Fidias E Leon-SarmientoZeng Y Wang
Nov 22, 2015·American Journal of Physiology. Heart and Circulatory Physiology·Denis S LoiselleAndrew James Taberner
Feb 16, 2010·The Journal of Experimental Biology·G A Lichtwark, C J Barclay
Nov 15, 2014·The Journal of Experimental Biology·Natalie C HoltGraham N Askew
Aug 4, 2009·The Journal of Experimental Biology·Elizabeth M DlugoszTheodore Garland
Mar 17, 2010·The Journal of Experimental Biology·Graham N AskewCharles P Ellington
Dec 23, 2011·The Journal of Experimental Biology·Natalie C Holt, Graham N Askew

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.