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SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance

Molecular Cell

Oct 3, 2019

Stephanie PanierSimon J. Boulton

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Abstract

Cancer cells acquire unlimited proliferative capacity by either re-expressing telomerase or inducing alternative lengthening of telomeres (ALT), which relies on telomere recombination. Here, we show that ALT recombination requires coordinate regulation of the SMX and BTR complexes to en...read more

Mentioned in this Paper

Alanine Transaminase
Bloom Syndrome
Cell Growth
Recombination, Genetic
Sulfamethoxazole
Telomere
Alanine Aminotransferase Measurement
Xeroderma Pigmentosum, Group F
Proliferation (Morphologic Abnormality)
Tumor Cells, Malignant
23
33
1
1
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SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance

Molecular Cell

Oct 3, 2019

Stephanie PanierSimon J. Boulton

PMID: 31447390

DOI: 10.1016/j.molcel.2019.07.010

Abstract

Cancer cells acquire unlimited proliferative capacity by either re-expressing telomerase or inducing alternative lengthening of telomeres (ALT), which relies on telomere recombination. Here, we show that ALT recombination requires coordinate regulation of the SMX and BTR complexes to en...read more

Mentioned in this Paper

Alanine Transaminase
Bloom Syndrome
Cell Growth
Recombination, Genetic
Sulfamethoxazole
23
33
1
1
Paper Details
References
  • References
  • Citations1
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.

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