SMALL ACIDIC PROTEIN1 acts with RUB modification components, the COP9 signalosome, and AXR1 to regulate growth and development of Arabidopsis.

Plant Physiology
Akari NakasoneYutaka Oono

Abstract

Previously, a dysfunction of the SMALL ACIDIC PROTEIN1 (SMAP1) gene was identified as the cause of the anti-auxin resistant1 (aar1) mutant of Arabidopsis (Arabidopsis thaliana). SMAP1 is involved in the response pathway of synthetic auxin, 2,4-dichlorophenoxyacetic acid, and functions upstream of the auxin/indole-3-acetic acid protein degradation step in auxin signaling. However, the exact mechanism by which SMAP1 functions in auxin signaling remains unknown. Here, we demonstrate that SMAP1 is required for normal plant growth and development and the root response to indole-3-acetic acid or methyl jasmonate in the auxin resistant1 (axr1) mutation background. Deletion analysis and green fluorescent protein/glutathione S-transferase pull-down assays showed that SMAP1 physically interacts with the CONSTITUTIVE PHOTOMORPHOGENIC9 SIGNALOSOME (CSN) via the SMAP1 F/D region. The extremely dwarf phenotype of the aar1-1 csn5a-1 double mutant confirms the functional role of SMAP1 in plant growth and development under limiting CSN functionality. Our findings suggest that SMAP1 is involved in the auxin response and possibly in other cullin-RING ubiquitin ligase-regulated signaling processes via its interaction with components associated wit...Continue Reading

References

Nov 1, 1990·The Plant Cell·C LincolnM Estelle
Jun 20, 1997·Science·T UlmasovT J Guilfoyle
Oct 29, 1997·Proceedings of the National Academy of Sciences of the United States of America·J KimA Theologis
Mar 9, 1999·The Plant Journal : for Cell and Molecular Biology·S J Clough, A F Bent
Dec 28, 1999·Proceedings of the National Academy of Sciences of the United States of America·J C del Pozo, M Estelle
Mar 29, 2000·Proceedings of the National Academy of Sciences of the United States of America·S R CutlerC R Somerville
Apr 19, 2003·The EMBO Journal·Sunethra DharmasiriMark Estelle
Oct 4, 2003·Plant Physiology·Yutaka OonoHirofumi Uchimiya
Jan 27, 2004·The Plant Cell·Shiv B TiwariTom J Guilfoyle
May 29, 2004·Trends in Plant Science·Nihal Dharmasiri, Mark Estelle
Mar 8, 2005·Trends in Plant Science·Mansour KarimiPierre Hilson
Mar 8, 2005·Annals of Botany·Andrew W Woodward, Bonnie Bartel
May 27, 2005·Nature·Nihal DharmasiriMark Estelle
May 27, 2005·Nature·Stefan Kepinski, Ottoline Leyser
Jul 5, 2005·Developmental Cell·Nihal DharmasiriMark Estelle
Aug 23, 2006·The Plant Journal : for Cell and Molecular Biology·Abidur RahmanYutaka Oono
Jan 16, 2007·Annals of Botany·Kate Dreher, Judy Callis
Jul 28, 2007·The Plant Journal : for Cell and Molecular Biology·Nihal DharmasiriM Estelle
Jan 22, 2008·Molecular Cell·Thimo KurzFrank Sicheri
May 1, 2008·Annual Review of Plant Biology·Sara K Hotton, Judy Callis
May 10, 2008·Plant Physiology·Esther Mirjam Natascha DohmannClaus Schwechheimer
Oct 15, 2008·Molecular Cell·Anjanabha Saha, Raymond J Deshaies
Jan 17, 2009·The Journal of Biological Chemistry·Johannes StuttmannLaurent D Noël
Mar 17, 2009·Trends in Plant Science·David E Somers, Sumire Fujiwara
Sep 15, 2009·Molecular Cell·Michael W SchmidtDieter A Wolf
Oct 24, 2009·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Jun-ya Kato, Noriko Yoneda-Kato
Dec 29, 2009·European Journal of Cell Biology·Claus Schwechheimer, Erika Isono
Dec 9, 2010·The Plant Cell·Silvia JuradoJuan C Del Pozo

❮ Previous
Next ❯

Citations

Aug 30, 2014·Journal of Experimental Botany·Nazila NazemofLaurian S Robert
Nov 19, 2013·Journal of Integrative Plant Biology·Yaling Song
Oct 13, 2015·Cell Reports·Shelly RozenMichal Sharon
Apr 30, 2015·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Shouvik DasSwarup K Parida
Apr 9, 2014·Frontiers in Plant Science·Julia Mergner, Claus Schwechheimer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.