Small animal positron emission tomography in food sciences

Amino Acids
R Bergmann, J Pietzsch

Abstract

Positron emission tomography (PET) is a 3-dimensional imaging technique that has undergone tremendous developments during the last decade. Non-invasive tracing of molecular pathways in vivo is the key capability of PET. It has become an important tool in the diagnosis of human diseases as well as in biomedical and pharmaceutical research. In contrast to other imaging modalities, radiotracer concentrations can be determined quantitatively. By application of appropriate tracer kinetic models, the rate constants of numerous different biological processes can be determined. Rapid progress in PET radiochemistry has significantly increased the number of biologically important molecules labelled with PET nuclides to target a broader range of physiologic, metabolic, and molecular pathways. Progress in PET physics and technology strongly contributed to better scanners and image processing. In this context, dedicated high resolution scanners for dynamic PET studies in small laboratory animals are now available. These developments represent the driving force for the expansion of PET methodology into new areas of life sciences including food sciences. Small animal PET has a high potential to depict physiologic processes like absorption, di...Continue Reading

References

Jan 1, 1977·Caries Research·J W Bawden, L E Hammarström
Jan 1, 1977·The International Journal of Applied Radiation and Isotopes·A P Wolf, C S Redvanly
Dec 1, 1977·The International Journal of Applied Radiation and Isotopes·S ReiffersH Wynberg
Jan 1, 1976·European Journal of Nuclear Medicine·D ComarC Marazano
Dec 30, 1976·European Journal of Nuclear Medicine·M MazièreG Berger
Feb 1, 1992·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·W VaalburgG J Meyer
Apr 1, 1992·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·A DaughertyS R Thorpe
Jan 1, 1991·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·K IshiwataY Mishima
Jan 11, 1991·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·F L OtsukaS A Wells
Sep 1, 1991·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·D J DoudetR M Cohen
Jan 1, 1990·International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes·A PlenevauxR Cantineau
Jan 1, 1986·International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes·H SharmaS Downey
Aug 1, 1989·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·R A HawkinsM E Phelps
Jan 1, 1988·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·R d'ArgyM Haaparanta
Jan 1, 1986·International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes·J M BolsterH Wynberg
Jan 1, 1986·International Journal of Nuclear Medicine and Biology·Y FujibayashiA Yokoyama
Apr 1, 1968·Archives of Biochemistry and Biophysics·K P McConnell, D M Roth
May 1, 1984·Calcified Tissue International·G M Whitford, D H Pashley
Mar 1, 1983·The International Journal of Applied Radiation and Isotopes·B MazièreA Syrota
Jan 1, 1983·International Journal of Nuclear Medicine and Biology·S C JonesJ M Taveras
Jan 1, 1983·European Journal of Nuclear Medicine·K KubotaH Yamaura
Feb 1, 1983·The Journal of Nutrition·A T NahapetianV R Young
May 1, 1993·Nuclear Medicine and Biology·R B Del RosarioR M Snider
Sep 1, 1993·International Journal of Radiation Biology·Y ArchimbaudR Masse

❮ Previous
Next ❯

Citations

Jun 25, 2009·Journal of Oncology·Franziska GrafJens Pietzsch
Oct 19, 2006·Nuclear Medicine and Biology·Christina HultschThomas Henle
Jun 29, 2013·Bioorganic & Medicinal Chemistry·Lorenzo CaputiRobert A Field

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.