Small bone lesions resembling erosions can frequently be found in bilateral wrist MRI of healthy individuals

Scandinavian Journal of Rheumatology
Kari PalosaariMarkku Hakala

Abstract

To examine magnetic resonance imaging (MRI) scans for bone lesions typical of rheumatoid arthritis (RA) in the wrist joints of healthy individuals. Thirty-one symptomless healthy persons (13/18 men/women), mean age 49 years (range 32-64 years), were included. MRI scans and radiographs of both wrists were obtained (62 wrists). The MRI scans and the radiographs were evaluated by two specialists according to the OMERACT recommendations and the Larsen method, respectively. MRI showed erosive-like lesions in either one or both wrists in 14 [45%, 95% confidence interval (CI) 27-64] out of 31 subjects. Altogether, 24 erosive-like changes were found in the 930 wrist bones evaluated (15 bones in each wrist). No more than two lesions per wrist were detected. All the changes were small (22 were grade 1 and two were grade 2; scale 0-10) and were found more often in the older subjects (55 vs. 43 years, p<0.001). Most lesions (54%) were located on the volar side of the wrist and adjacent to the ligament insertions. Intravenous administration of the contrast medium gadolinium diethylenetriaminepentaacetate (Gd-DTPA) was used in 10 subjects, and mild to moderate Gd-DTPA enhancement in the synovial compartments was seen in six of them: five had...Continue Reading

References

Jun 22, 2002·AJR. American Journal of Roentgenology·B PartikT H Helbich
Mar 15, 2006·Skeletal Radiology·P L RobertsonG J McColl

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Citations

Jan 22, 2013·Annals of the Rheumatic Diseases·Annemarie KrabbenAnnette H M van der Helm-van Mil
Dec 4, 2013·Scandinavian Journal of Rheumatology·W StompM Reijnierse
Apr 11, 2014·Annals of the Rheumatic Diseases·Hanna W van SteenbergenAnnette H M van der Helm-van Mil
Mar 2, 2018·Annals of the Rheumatic Diseases·Debbie M BoetersAnnette H M van der Helm-van Mil

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