Small bowel gastrointestinal stromal tumor: a retrospective study of 32 cases at a single center and review of the literature

Therapeutics and Clinical Risk Management
Lei ZhouShengbin Sun

Abstract

Gastrointestinal stromal tumor (GIST) is a rare tumor of the small bowel, which can be difficult to diagnose and has a varied clinical outcome. This is a retrospective review of the diagnosis, management, and clinical outcome of 32 patients diagnosed with primary small bowel GIST from a single center and a comparison of the findings with previously published cases. Retrospective review of data from patient clinical records, endoscopic and imaging findings, surgical procedures, tumor histology and immunohistochemistry, and clinical outcome was conducted. Data of 32 patients with a median age of 56 years including 50% men and women were reviewed. The majority (29/32) were symptomatic at presentation, with the main symptom being gastrointestinal bleeding (15/32). Imaging detection rates included ultrasound (0%), magnetic resonance imaging (0%), computed tomography (54.8%), computed tomography angiography (71.4%), and double-balloon enteroscopy (88.9%). The mean tumor diameter was 5.3 cm; 4 tumors were located in the duodenum, 21 in the jejunum, and 7 in the ileum. Based on the tumor size and mitotic index, 5 (15.6%), 15 (46.9%), 0 (0%), and 12 (37.5%) patients were classified into very low-risk, low-risk, intermediate-risk, and hi...Continue Reading

Citations

Jun 18, 2019·World Journal of Gastrointestinal Endoscopy·Tomofumi HorieTakanori Kanai
Mar 22, 2021·Gastrointestinal Endoscopy Clinics of North America·Richard M Wu, Laurel R Fisher

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Methods Mentioned

BETA
light microscopy
surgical resection
biopsy
SMA

Software Mentioned

SPSS

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