PMID: 9659165Jul 11, 1998Paper

Small bowel transit of a bran meal residue in humans: sieving of solids from liquids and response to feeding

Gut
J M HebdenR C Spiller

Abstract

Ileal motor patterns are adapted to the propulsion of viscous meal residue, such as bran, which accumulates in the distal ileum postprandially. To examine the effects of a second liquid/solid meal on ileal emptying. Eleven healthy fasting subjects consumed a 1.47 MJ pancake containing 15 g bran and 5 MBq Technetium-99m labelled amberlite resin (meal A). Gastric emptying and transit through the left upper quadrant (proximal) and right lower quadrant (distal) small bowel regions and colon were assessed scintigraphically. Transit was compared with and without a second Indium-111 liquid/solid DTPA labelled 2.28 MJ meal (B) given three hours after the first meal. Gastric emptying of meal A was slower than meal B (the time for 50% of the activity to leave the stomach (T50) being 113 (11) minutes versus 48 (3) minutes respectively, p < 0.01, n = 11). Both meals passed rapidly through the proximal small bowel (T50 meal A = 57 (14) minutes versus T50 meal B = 42 (11) minutes). Transit of meal A through the distal small bowel was much slower (T50 more than 390 minutes versus 176 (29) minutes for meal B, p < 0.01), resulting in meal B overtaking meal A and entering the colon earlier. Ingestion of the second meal (B) resulted in significan...Continue Reading

References

Jul 2, 1994·Lancet·C Y Francis, P J Whorwell
Oct 1, 1957·The Journal of Clinical Investigation·B BORGSTROMJ SJOVALL

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Citations

Apr 11, 2008·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·R G Lentle, P W M Janssen
Jul 1, 2005·Digestive Diseases and Sciences·Henry C LinUNKNOWN AMS Task Force Committee on Gastrointestinal Transit
Dec 2, 2009·Digestive Diseases and Sciences·Annemie DeiterenAlan R Zinsmeister
Jan 30, 2010·Critical Reviews in Food Science and Nutrition·Roger G Lentle, Patrick W M Janssen
Jul 28, 2013·International Journal of Colorectal Disease·S Vande VeldeS Van Biervliet
Nov 15, 2007·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·R SadikH Abrahamsson
Jun 20, 2006·Best Practice & Research. Clinical Gastroenterology·Fernando Fernández-Bañares
Dec 25, 2016·International Journal of Biometeorology·Taner DandinogluUygar Teomete
Mar 1, 2018·The Journal of Nutrition·Carlos A MontoyaPaul J Moughan
Oct 25, 2021·Gastroenterology·Anthony J TreichelArthur Beyder

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