Small cell carcinoma arising in Barrett's esophagus: a case report and review of the literature.

Journal of Medical Case Reports
Haridimos MarkogiannakisStilianos Katsaragakis

Abstract

Gastrointestinal tract small cell carcinoma is an infrequent and aggressive neoplasm that represents 0.1-1% of gastrointestinal malignancies. Very few cases of small cell esophageal carcinoma arising in Barrett's esophagus have been reported in the literature. An extremely rare case of primary small cell carcinoma of the distal third of the esophagus arising from dysplastic Barrett's esophagus is herein presented. A 62-year-old man with gastroesophageal reflux history presented with epigastric pain, epigastric fullness, dysphagia, anorexia, and weight loss. Esophagogastroscopy revealed an ulceroproliferative, intraluminar mass in the distal esophagus obstructing the esophageal lumen. Biopsy showed small cell esophageal carcinoma. Contrast-enhanced chest and abdominal computed tomography demonstrated a large tumor of the distal third of the esophagus without any lymphadenopathy or distant metastasis. Preoperative chemotherapy with cisplatine and etoposide for 3 months resulted in a significant reduction of the tumor. After en block esophagectomy with two field lymph node dissection, proximal gastrectomy, and cervical esophagogastric anastomosis, the patient was discharged on the 14th postoperative day. Histopathology revealed a ...Continue Reading

References

Oct 28, 1999·Archives of Pathology & Laboratory Medicine·M C Saint Martin, G Chejfec
Aug 17, 2000·Diagnostic Cytopathology·K T Chen
Mar 20, 2003·The Annals of Thoracic Surgery·Gouri H PantvaidyaRamakant K Deshpande
Jul 2, 2003·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·Tsuyoshi NoguchiShigeo Yokoyama
Oct 1, 1952·The Journal of Pathology and Bacteriology·F MCKEOWN

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Citations

Mar 19, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mao-Bin MengWang Ping
Aug 28, 2020·Clinical Journal of Gastroenterology·Tsubasa KinoshitaTakashi Yao
Aug 27, 2021·World Journal of Clinical Cases·Yong-Hui WuJian Zhang

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Methods Mentioned

BETA
surgical resection
dissection

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