PMID: 26331396Sep 4, 2015Paper

Small cell carcinoma of the bladder: Our experience

Archivos españoles de urología
Laura Pesquera-OrtegaJosé Ramón Cortiñas-González

Abstract

Small cell carcinoma of the bladder shows low incidence and poor survival; thus, treatment algorithms based on randomized studies are unavailable. The aim of the present study is to review our case series. Observational retrospective study of 10 patients diagnosed with small cell carcinoma of the bladder between 2006 and 2013. Mean age was 65.7 years; There was only one female in the cohort. In all cases hematuria was the fist symptom. 4 cases presented high-grade papillary urothelial carcinoma with small cell carcinoma. Radical cystectomy was performed in 40% patients, in combination with chemotherapy, radiotherapy or both. Median survival was 330 days (IC 95%: 40.757- 619.243) and only one patient showed complete response. Even when small cell carcinoma of the bladder is a low incidence tumor, its prognosis is worse than that of urothelial carcinoma. Although further randomized studies are needed to best define treatment, this study shows that survival at local stages is optimized by neoadjuvant chemotherapy, followed by radical resection, as the literature suggests.

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
J Dunst
Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
J KattanA Lusinchi
Reviews in Urology
Shailen S SehgalThomas J Guzzo
© 2021 Meta ULC. All rights reserved