PMID: 9179055Jun 1, 1997Paper

Small cell osteosarcoma of bone. Review of 72 cases

Cancer
H NakajimaK K Unni

Abstract

Small cell osteosarcoma of bone is a rare form of osteosarcoma, with an incidence rate of 1.3%. This tumor must be differentiated from other small cell malignancies because of treatment considerations, particularly patient response to chemotherapy. Clinicopathologic findings in 72 cases (22 from Mayo Clinic files and 50 from consultation files) of small cell osteosarcoma of bone were studied. The femur was the most common bone involved, although the tumor was found in all portions of the skeleton. Radiographic features (available in 35 cases) suggested a diagnosis of osteosarcoma in 20 cases, Ewing's sarcoma or lymphoma in 14 cases, and giant cell tumor in 1 case. Histologically, there were four types according to the predominant cell size and cytologic features. Osteoid production was identified in all tumors. Complete treatment and follow-up data were available for 45 cases. Generally, in those cases without surgical treatment, greater than 60% of patients died of disease within 2 years. If the surgical procedure was associated with a marginal tumor margin, the prognosis was poor. In the 30 patients with wide or radical surgical margins, at last follow-up 13 were alive with no evidence of disease, 2 were alive with disease, a...Continue Reading

References

Dec 15, 1989·Cancer·F BertoniM Campanacci
Nov 1, 1988·International Journal of Radiation Oncology, Biology, Physics·B SteaT J Kinsella
Jan 1, 1987·Skeletal Radiology·J EdeikenH C Carrasco
Jan 1, 1988·Archives of Orthopaedic and Trauma Surgery·B SanjayG Vishwakarma
Jan 1, 1966·Cancer·R V HutterR S Sherman
Sep 1, 1982·Cancer·S E MartinJ Costa

❮ Previous
Next ❯

Citations

Dec 2, 2011·Der Orthopäde·R von Eisenhart-RotheH Rechl
Nov 13, 2010·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Gail YarmishSinchun Hwang
Nov 6, 2003·Journal of Clinical Pathology·K OkadaE Itoi
Aug 10, 2006·International Orthopaedics·Dorothe Carrle, Stefan S Bielack
May 15, 2009·Archives of Orthopaedic and Trauma Surgery·Erol YalnizOmer Yalçin
Jul 7, 2012·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Andrew E HorvaiRichard J O'Donnell
Apr 1, 2014·Seminars in Diagnostic Pathology·Jeffery T Green, Anne M Mills
Apr 1, 2014·Seminars in Diagnostic Pathology·Eun-Young K ChoiRajiv M Patel
Mar 1, 2012·Surgical Pathology Clinics·Justin L Seningen, Carrie Y Inwards
Apr 17, 2010·American Journal of Clinical Pathology·Justin A BishopSyed Z Ali
Sep 11, 1998·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·K K Unni
Jan 19, 2007·Head & Neck·Joseph RinaggioH Stan McGuff
Oct 12, 2011·Genes, Chromosomes & Cancer·Larisa V DebelenkoSusana C Raimondi
Jun 10, 2004·Human Pathology·Yuichiro OshimaYasuo Hirayama
Jul 25, 2006·Cancer Treatment Reviews·Alessandra LonghiGaetano Bacci
Aug 1, 2015·Journal of Cytology·Uma HandaSudhir Kumar Garg
Apr 28, 2012·European Journal of Radiology·Cheng-Sheng WangKe-Min Chen
Feb 28, 2015·The American Journal of Surgical Pathology·Alberto RighiAngelo Paolo Dei Tos
Jun 4, 2016·Der Radiologe·B Jobke, M Werner
Nov 13, 2003·Clinical Orthopaedics and Related Research·Andrew JawaJohn P Dormans
Apr 10, 2018·SICOT-J·Amirhossein MisaghiAnna A Kulidjian
Oct 10, 2008·Der Pathologe·K HauptmannK-D Schaser
Apr 6, 2006·Virchows Archiv : an International Journal of Pathology·Jun NishioJulia A Bridge
Jul 22, 2004·The Oncologist·Neyssa MarinaRichard Gorlick
Jan 6, 2006·Clinical Orthopaedics and Related Research·Brandon A RamoDouglas J McDonald
May 8, 2001·Cancer Investigation·W S Ferguson, A M Goorin
Apr 12, 2000·Cancer Control : Journal of the Moffitt Cancer Center·D LetsonC A Muro-Cacho
Aug 5, 2009·The Journal of the American Academy of Orthopaedic Surgeons·Patrick J MesserschmittPatrick J Getty
May 4, 2010·Applied Immunohistochemistry & Molecular Morphology : AIMM·Empar MayordomoAntonio Llombart-Bosch
Dec 25, 2009·Advances in Anatomic Pathology·Shaoying Li, Gene P Siegal
Mar 5, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Colleen M CostelloeEdith M Marom
Feb 8, 2007·Archives of Pathology & Laboratory Medicine·Meera Hameed
Feb 8, 2007·Archives of Pathology & Laboratory Medicine·Andrea T Deyrup, Anthony G Montag
Mar 6, 2008·Archives of Pathology & Laboratory Medicine·Armita BahramiJae Y Ro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.