Small-for-gestational age and large-for-gestational age thresholds to predict infants at risk of adverse delivery and neonatal outcomes: are current charts adequate? An observational study from the Born in Bradford cohort

BMJ Open
T NorrisNoel Cameron

Abstract

Construct an ethnic-specific chart and compare the prediction of adverse outcomes using this chart with the clinically recommended UK-WHO and customised birth weight charts using cut-offs for small-for-gestational age (SGA: birth weight <10th centile) and large-for-gestational age (LGA: birth weight >90th centile). Prospective cohort study. Born in Bradford (BiB) study, UK. 3980 White British and 4448 Pakistani infants with complete data for gestational age, birth weight, ethnicity, maternal height, weight and parity. Prevalence of SGA and LGA, using the three charts and indicators of diagnostic utility (sensitivity, specificity and area under the receiver operating characteristic (AUROC)) of these chart-specific cut-offs to predict delivery and neonatal outcomes and a composite outcome. In White British and Pakistani infants, the prevalence of SGA and LGA differed depending on the chart used. Increased risk of SGA was observed when using the UK-WHO and customised charts as opposed to the ethnic-specific chart, while the opposite was apparent when classifying LGA infants. However, the predictive utility of all three charts to identify adverse clinical outcomes was poor, with only the prediction of shoulder dystocia achieving an...Continue Reading

References

Feb 1, 1992·Lancet·J GardosiE M Symonds
Jul 1, 1992·Statistics in Medicine·T J Cole, P J Green
Oct 1, 1991·Radiology·F P HadlockJ Martinez-Poyer
Mar 5, 1994·BMJ : British Medical Journal·T J Cole
Sep 1, 1995·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J GardosiA Chang
Aug 21, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·B ClaussonS Cnattingius
Sep 25, 2001·American Journal of Obstetrics and Gynecology·B A DoctorM Hack
Mar 29, 2002·American Journal of Public Health·Saffron Karlsen, James Y Nazroo
Apr 9, 2004·Food and Nutrition Bulletin·Mercedes de OnisJose Martines
Sep 25, 2004·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Lesley McCowanJason Gardosi
Jun 14, 2005·The New England Journal of Medicine·Caroline A CrowtherUNKNOWN Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group
Jul 28, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Lesley M E McCowanAlistair W Stewart
Dec 21, 2006·CJEM·Jerome FanAndrew Worster
Mar 16, 2007·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Max MongelliJason Gardosi
Mar 24, 2007·BJOG : an International Journal of Obstetrics and Gynaecology·X ZhangM S Kramer
Sep 20, 2007·BJOG : an International Journal of Obstetrics and Gynaecology·J GardosiA Francis
Jan 9, 2008·BMC Pregnancy and Childbirth·William J KieransMichael S Kramer
Mar 12, 2008·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Jeltsje S CnossenKhalid S Khan
Oct 1, 2008·BJOG : an International Journal of Obstetrics and Gynaecology·J A HutcheonR W Platt
Dec 24, 2010·Annals of Human Biology·Tim J ColeUNKNOWN RCPCH Growth Chart Expert Group
Jul 28, 2011·Neonatology·Sarah E SeatonBradley N Manktelow
Feb 22, 2012·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Joel G RayMarcelo L Urquia
Feb 24, 2012·Diabetes Care·Patrick M CatalanoUNKNOWN HAPO Study Cooperative Research Group
Apr 3, 2012·American Journal of Obstetrics and Gynecology·Gaea Schwaebe MooreGuibo Xing
May 1, 2012·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Hyun-Hwa ChaJong-Hwa Kim
Sep 14, 2012·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Gillian E Hanley, Patricia A Janssen
Oct 16, 2012·International Journal of Epidemiology·John WrightUNKNOWN Born in Bradford Scientific Collaborators Group
Jun 26, 2013·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Tai-Ho HungJenn-Jeih Hsu
Jul 3, 2013·American Journal of Obstetrics and Gynecology·Gillian E Hanley, Patricia A Janssen
Feb 13, 2014·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Jennifer Hutcheon

❮ Previous
Next ❯

Citations

Oct 11, 2015·Best Practice & Research. Clinical Obstetrics & Gynaecology·Marcelo L UrquiaSusitha Wanigaratne
Aug 4, 2016·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·B PoljakA Sharp
Dec 10, 2016·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G ChiossiG R Saade
Sep 11, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ruofan YaoOzhan M Turan
Dec 20, 2017·Journal of Perinatal Medicine·Elena SpadaFabio Facchinetti
Sep 3, 2019·Paediatric and Perinatal Epidemiology·Stephanie K Y ChoiGeorgina M Chambers
Jan 24, 2017·Transplantation·Giorgina Barbara PiccoliUNKNOWN Italian Study group on Kidney and Pregnancy of the Italian Society of Nephrology. Working Group on Pregnancy in Renal Transp
Jun 15, 2019·Archives of Disease in Childhood·Anna Freni-SterrantinoAnna Hansell
Aug 28, 2019·Nutrients·Luis Pereira-da-SilvaChristoph Fusch
Oct 31, 2020·Paediatric and Perinatal Epidemiology·Melissa A JonesBethany Barone Gibbs
Apr 21, 2021·American Journal of Perinatology·Lia CorreiaLuís Pereira-da-Silva

❮ Previous
Next ❯

Methods Mentioned

BETA
SGA

Software Mentioned

LMSchartmaker Light
Stata
Customised Centile Calculator

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.